Monoclonal antibodies in rheumatoid arthritis

CohenM.; OmairM.A.; KeystoneE.C.

首页> 外文期刊>International journal of clinical rheumatology. >Monoclonal antibodies in rheumatoid arthritis

【24h】

Monoclonal antibodies in rheumatoid arthritis

机译：类风湿关节炎的单克隆抗体

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Monoclonal antibodies are a group of complex and effective biologic agents used in the treatment of rheumatoid arthritis and other immune-mediated inflammatory diseases. They now represent an important series of options in the treatment of rheumatoid arthritis. In this review, we discuss the efficacy and safety of these agents. In addition, information regarding upcoming monoclonal agents and biosimilars is presented.

机译：单克隆抗体是一组用于治疗类风湿关节炎和其他免疫介导的炎症性疾病的复杂有效的生物制剂。现在，它们代表了类风湿关节炎治疗中的一系列重要选择。在这篇综述中，我们讨论了这些药物的功效和安全性。此外，还介绍了有关即将到来的单克隆药物和生物仿制药的信息。

著录项

来源
《International journal of clinical rheumatology.》 |2013年第5期|共16页
作者
CohenM.; OmairM.A.; KeystoneE.C.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类全身性疾病;
关键词
adalimumab; anakinra; anakinra safety; B-cell depletion therapy; certolizumab; golimumab; IL-1 inhibition; IL-6 inhibition; infliximab; monoclonal antibody; rheumatoid arthritis treatment; rituximab; TNF inhibition safety; TNF inhibitors; tocilizumab; tocilizumab safety;

机译：阿达木单抗;anakinra;anakinra安全;B细胞耗竭疗法;西妥珠单抗;golimumab;IL-1抑制;IL-6抑制;英夫利昔单抗;单克隆抗体;类风湿关节炎治疗;利妥昔单抗;TNF抑制安全性;TNF抑制剂;托珠单抗;托珠单抗安全性;

相似文献

外文文献
中文文献
专利

1. Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. [J] . Nandakumar KS, Holmdahl R Journal of Immunological Methods . 2005,第1a2期

机译：使用四种对胶原诱导的关节炎和类风湿关节炎都公认的主要表位具有特异性的单克隆抗体，可以有效地促进胶原抗体诱导的关节炎（CAIA）。
2. Golimumab, a Human Anti-Tumor Necrosis Factor alpha Monoclonal Antibody, Injected Subcutaneously Every Four Weeks in Methotrexate-Naive Patients With Active Rheumatoid Arthritis Twenty-Four-Week Results of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Golimumab Before Methotrexate as First-Line Therapy for Early-Onset Rheumatoid Arthritis (vol 60, pg 2272, 2009) [J] . Emery Arthritis and Rheumatism . 2010,第9期

机译：Golimumab是一种人类抗肿瘤坏死因子α单克隆抗体，每四周一次皮下注射纯净甲氨蝶呤的活动性类风湿性关节炎患者，III期，多中心，随机，双盲，安慰剂对照研究的二十四周结果甲氨tre呤之前戈利木单抗作为早期治疗类风湿关节炎的一线治疗方法的研究（第60卷，第2272页，2009年）
3. Golimumab, a Human Anti-Tumor Necrosis Factor alpha Monoclonal Antibody, Injected Subcutaneously Every Four Weeks in Methotrexate-Naive Patients With Active Rheumatoid Arthritis Twenty-Four-Week Results of a Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Golimumab Before Methotrexate as First-Line Therapy for Early-Onset Rheumatoid Arthritis (vol 60, pg 2272, 2009) [J] . Emery Arthritis and Rheumatism . 2010,第9期

机译：Golimumab是一种人类抗肿瘤坏死因子α单克隆抗体，每四周一次皮下注射纯净甲氨蝶呤的活动性类风湿性关节炎患者，III期，多中心，随机，双盲，安慰剂对照研究的二十四周结果甲氨tre呤之前戈利木单抗作为早期治疗类风湿关节炎的一线治疗方法的研究（第60卷，第2272页，2009年）
4. Development of a Protease-Activated Antibody That Reduces the Side-Effects of Rheumatoid Arthritis (RA) Therapy [C] . Tian-Lu Cheng, Chih-Hung Chuang Protein Engineering Summit. . 2018

机译：蛋白酶活化抗体的研制降低了类风湿性关节炎（RA）治疗的副作用
5. Monoclonal antibody therapy of rheumatoid arthritis. [D] . Hammaker, Deepa Rajan. 1999

机译：类风湿关节炎的单克隆抗体治疗。
6. Golimumab: A novel human anti-TNF-α monoclonal antibody for the treatment of rheumatoid arthritis ankylosing spondylitis and psoriatic arthritis [O] . Jonathan Kay, Mahboob U Rahman 2009

机译：戈利木单抗：一种新型人类抗TNF-α单克隆抗体用于治疗类风湿性关节炎强直性脊柱炎和银屑病关节炎
7. Golimumab, a human anti-tumor necrosis factor alpha monoclonal antibody, injected subcutaneously every four weeks in methotrexate-naive patients with active rheumatoid arthritis : twenty-four-week results of a phase III, multicenter, randomized, double-blind, placebo-controlled study of golimumab before methotrexate as first-line therapy for early-onset rheumatoid arthritis. [O] . Emery, Paul, Fleischmann, Roy M, Moreland, Larry W, 2009

机译：Golimumab是一种人类抗肿瘤坏死因子α单克隆抗体，每4周一次向未接受甲氨蝶呤治疗的活动性类风湿关节炎患者皮下注射：III期，多中心，随机，双盲，安慰剂对照的24周结果甲氨蝶呤前戈利木单抗作为早期治疗类风湿关节炎的一线治疗的研究。

Monoclonal antibodies in rheumatoid arthritis

摘要

著录项

相似文献

相关主题

期刊订阅