首页> 外文期刊>International journal of clinical rheumatology. >Assessment of sleep health in patients with rheumatic disease
【24h】

Assessment of sleep health in patients with rheumatic disease

机译:风湿病患者睡眠健康评估

获取原文
获取原文并翻译 | 示例
           

摘要

Rheumatology clinic patients frequently experience sleep disturbances and poor sleep. Increased frequencies of primary sleep disorders, including obstructive sleep apnea and restless legs syndrome, have been reported in rheumatic disease patient populations. Disturbed sleep with fragmentation is commonly observed and has been associated with pain, depression and increased inflammatory disease activity. In recent years, there has been increased investigation into relationships between sleep regulation and inflammatory mediators. The role of TNF-alpha in sleep physiology and pathology has been intensively studied. The generally positive effect of biologic agents such as anti-TNF-a therapy on sleep in rheumatology patients has been observed in polysomnographic studies and in larger clinical trials. In this article we review the primary sleep disorders with reference to the rheumatology patient, provide an overview of sleep regulation with specific attention to inflammatory cytokine influences and discuss the approach to sleep problems for the rheumatology clinic patient.
机译:风湿病门诊患者经常会出现睡眠障碍和睡眠不足。在风湿性疾病患者人群中,原发性睡眠障碍(包括阻塞性睡眠呼吸暂停和不安腿综合征)的发生频率有所增加。通常观察到睡眠不稳和破碎,并与疼痛,抑郁和炎性疾病活动增加有关。近年来,对睡眠调节与炎症介质之间关系的研究越来越多。 TNF-α在睡眠生理和病理学中的作用已得到深入研究。在多导睡眠图研究和更大的临床试验中,已观察到生物制剂(例如抗TNF-α治疗)对风湿病患者睡眠的总体积极作用。在本文中,我们针对风湿病患者回顾了原发性睡眠障碍,提供了对睡眠调节的概述,并特别关注了炎症性细胞因子的影响,并讨论了风湿病临床患者的睡眠问题解决方法。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号