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首页> 外文期刊>British journal of ophthalmology >Novel device for expanding Schlemm's canal: a morphological study
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Novel device for expanding Schlemm's canal: a morphological study

机译：新型Schlemm根管扩张器：形态学研究

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摘要

This study was performed to assess any changes in Schlemm's canal (SC) in human autopsy eyes possibly resulting from the injection of a viscoelastic substance and implantation of a new device (the Stegmann Canal Expander, SCE) into SC. After the surgical procedure, eyes were fixed, dissected into quartered segments and examined using light and scanning electron microscopy. Tissue sections displayed a marked dilation of SC and of the collector channels compared with untreated control sections. The SC walls were disrupted in some areas due to viscodilation, but not due to SCE implantation. In all eyes, the entire 9-mm length of the SCE was positioned inside the canal, keeping the canal wide open. The SCE diameter of 240 mu m remained unchanged after implantation. Injection of a viscoelastic substance into SC leads to marked dilation of SC and collector channels. Implanting the SCE into SC allowed persistent expansion of SC and stretching of the trabecular meshwork. This may increase the permeability of the trabecular meshwork, reduce its resistance to aqueous humour and maintain circumferential flow within SC. Experimental and clinical studies should determine the impact of this new canal expander in terms of lowering intraocular pressure in glaucoma surgery.
机译：进行这项研究的目的是评估可能由注射粘弹性物质和向SC植入新装置（Stegmann Canal Expander，SCE）引起的人类尸检眼Schlemm运河（SC）的任何变化。手术后，将眼睛固定，切成四等分，并用光和扫描电子显微镜检查。与未处理的对照切片相比，组织切片显示SC和收集通道明显扩张。 SC壁在某些区域由于粘膜扩张而不是由于SCE植入而破裂。在所有人的眼中，SCE的整个9毫米长都位于根管内，使根管保持张开状态。植入后SCE直径为240μm保持不变。将粘弹性物质注入SC会导致SC和收集器通道明显扩张。将SCE植入SC可使SC持续扩张并拉伸小梁网。这可能会增加小梁网的渗透性，降低其对房水的抵抗力并维持SC内的周向流动。实验和临床研究应确定这种新的扩张管在青光眼手术中降低眼内压方面的影响。

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