...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of colorectal disease. >Poor symptomatic relief and quality of life in patients treated for 'solitary rectal ulcer syndrome without external rectal prolapse'.
【24h】

Poor symptomatic relief and quality of life in patients treated for 'solitary rectal ulcer syndrome without external rectal prolapse'.

机译：“没有外部直肠脱垂的孤立性直肠溃疡综合征”患者的症状缓解和生活质量差。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Solitary rectal ulcer syndrome (SRUS) is a chronic disabling condition. Several therapeutic options have been advocated including conservative approaches and surgery, bringing into question their functional outcomes. This study aimed to assess treatment procedures on both anorectal complaints and quality of life (QoL) using standardised self-administered questionnaires. MATERIALS AND METHODS: Forty-one patients who underwent treatments for SRUS in two referral centres were reviewed. A standardised self-administered questionnaire including incontinence (Cleveland Clinic), constipation (Knowles-Eccersley-Scott symptom, KESS) and gastrointestinal quality of life index validated scoring systems was mailed to each patient (median follow-up, 36 months). Correlation between treatment options, functional results and quality of life was analysed. RESULTS: The mean Cleveland Clinic and KESS scores were respectively 5.3+/-5.8 (normal 0) and 19.1+/-8 (normal<9). The mean QoL score reached 89+/-28.8 (normal 125). A linear correlation between the QoL score and functional results was observed. There was no influence of treatment options on QoL results. A multivariate analysis identified five parameters predictive of a better QoL: presence of paradoxical puborectalis contraction, absence of descending perineum, absence of procidentia, age<40 and treatment exclusively based on laxatives. CONCLUSION: Despite several therapeutic options including surgery, patients with SRUS still frequently complain of disturbed anorectal function and significant alteration of their QoL.
机译：背景：孤立性直肠溃疡综合征（SRUS）是一种慢性致残性疾病。已经提倡了几种治疗选择，包括保守疗法和手术，使它们的功能结局受到质疑。这项研究旨在使用标准化的自我管理问卷来评估肛肠主诉和生活质量（QoL）的治疗程序。材料与方法：回顾了在两个转诊中心接受过SRUS治疗的41例患者。已向每位患者邮寄了包括尿失禁（克利夫兰诊所），便秘（Knowles-Eccersley-Scott症状，KESS）和胃肠道生活质量指数验证评分系统的标准化自我管理问卷（中位随访时间为36个月）。分析了治疗方案，功能结果和生活质量之间的相关性。结果：Cleveland Clinic和KESS的平均得分分别为5.3 +/- 5.8（正常0）和19.1 +/- 8（正常<9）。 QoL平均得分达到89 +/- 28.8（正常为125）。观察到QoL得分与功能结果之间的线性相关性。治疗选择对生活质量的结果没有影响。一项多变量分析确定了预测QoL更好的五个参数：耻骨直肠反常收缩，会阴部下降，无偶然性，年龄<40岁以及完全基于泻药的治疗。结论：尽管有包括手术在内的多种治疗选择，但SRUS患者仍经常抱怨肛门直肠功能受阻以及QoL明显改变。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号