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首页> 外文期刊>International journal of colorectal disease. >Segmental colitis associated with diverticulosis: A 5-year follow-up
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Segmental colitis associated with diverticulosis: A 5-year follow-up

机译:与憩室病相关的节段性结肠炎:5年随访

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Background and aims Literature data about the outcome of segmental colitis associated with diverticulosis (SCAD) are scarce. Our aim was to assess the clinical outcome of SCAD according to the type of disease. Patients/methods Twenty-seven SCAD patients underwent a 5-year follow-up (13 males, 14 females; mean age, 63.71 years; range, 50-85 years). Eleven patients were affected by type A, eight by type B, four by type C and four by type D SCAD. During the follow-up, all type B, C, and D patients were under continuous medical treatment. Five type A patients refused any maintaining treatment, but accepted to undergo the clinical, endoscopic, and histological follow-up. Results/findings Five type A patients taking therapy (83.33%), two type A not taking therapy (50%), all type C patients (100%), five type B patients (62.5%) and none of type D (0%) were under continuous remission at the end of the follow-up. All type D patients required further steroid course to obtain remission, and two patients required azathioprine to maintain remission. Interpretations/conclusions SCAD B and D patients fail to maintain long-term remission, often requiring immunosuppressive treatment. SCAD A and C patients show a more benign course; however, long-term treatment guarantees longer remission also in those patients.
机译:背景与目的关于与憩室病(SCAD)相关的节段性结肠炎的结局文献资料很少。我们的目的是根据疾病类型评估SCAD的临床结局。患者/方法对27位SCAD患者进行了5年的随访(男性13例,女性14例;平均年龄63.71岁;范围50-85岁)。 SCAD影响了11例患者,A型影响了8位患者,B型影响了8位患者,C型影响了4位患者,D型影响了4位患者。在随访期间,所有B型,C型和D型患者均接受持续治疗。五名A型患者拒绝接受任何维持治疗,但接受了临床,内镜和组织学随访。结果/发现5例接受治疗的A型患者(83.33%),2例未接受治疗的A型患者(50%),所有C型患者(100%),5例B型患者(62.5%)和D型均不接受(0% )在随访结束时持续缓解。所有D型患者都需要进一步接受类固醇激素治疗才能获得缓解,而两名患者需要硫唑嘌呤来维持缓解。解释/结论SCAD B和D患者无法维持长期缓解,通常需要进行免疫抑制治疗。 SCAD A和C患者表现出更好的病程;然而,长期治疗也保证了这些患者的更长的缓解期。

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