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首页> 外文期刊>International journal of computational biology and drug design >Understanding the lac operon with GeneAct
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Understanding the lac operon with GeneAct

机译：通过GeneAct了解lac操纵子

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摘要

GeneAct is a new framework developed to accelerate the coding of interactive programs for learning genetics. In this paper, the framework is used to create an interactive program for understanding the lac operon. Gene regulation, an inherent property of all organisms, is responsible for growth and development, as well as for an organism's ability to respond to changes in the environment. To illustrate the mechanisms of gene regulation, we highlight the operon system in bacteria because it is well defined and has widely been investigated. The control of the genes of the lac operon depends upon the availability of - and the nature of - the carbon source used for energy metabolism in bacteria. The interactive program based on GeneAct provides clearly defined tutorial tools for: 1) reading and thinking about the subject; 2) visualising the processes involved in regulating genes; 3) controlling the various molecular elements in the processes.
机译：GeneAct是一个新框架，旨在加速学习遗传学的交互式程序的编码。在本文中，该框架用于创建一个交互式程序，以了解lac操纵子。基因调节是所有生物的固有属性，它负责生长和发育以及生物对环境变化的响应能力。为了说明基因调控的机制，我们着重介绍了细菌中的操纵子系统，因为它定义明确并且已得到广泛研究。紫胶操纵子基因的控制取决于细菌中能量代谢所用碳源的可用性和性质。基于GeneAct的交互式程序提供了明确定义的教程工具，用于：1）阅读和思考该主题; 2）可视化调节基因的过程; 3）控制过程中的各种分子元素。

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