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首页> 外文期刊>International journal of endocrinology >High Prevalence of Infertility among Women with Graves' Disease and Hashimoto's Thyroiditis
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High Prevalence of Infertility among Women with Graves' Disease and Hashimoto's Thyroiditis

机译：格雷夫斯氏病和桥本甲状腺炎妇女的不孕症高发

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Objectives. To evaluate the prevalence of infertility in women with Graves' disease (GD) or Hashimotos thyroiditis (HT) and associated factors. Material and Methods. This cross-sectional study was conducted at the Endocrinology Clinic for Thyroid Autoimmune Diseases, with 193 women aged 18-50 years with GD and 66 women aged 18-60 years with HT. The women were interviewed to obtain data on their gynecological and obstetric history and family history of autoimmune diseases. Their medical records were reviewed to determine the characteristics of the disease and to confirm association with other autoimmune diseases. Infertility was defined as 12 months of unprotected sexual intercourse without conception. Results. The prevalence of infertility was 52.3% in GD and 47.0% in HT. Mean age at diagnosis was 36.5 years and 39.2 years, in GD and HT, respectively. The mean number of pregnancies was lower in women who were 35 years old or younger at diagnosis and was always lower following diagnosis of the disease, irrespective of age. The only variable associated with infertility was a shorter time of the disease in HT. Conclusions. The prevalence of infertility was high in women with GD and HT and affected the number of pregnancies in young women.
机译：目标。评估患有Graves病（GD）或桥本甲状腺炎（HT）的妇女的不育患病率及相关因素。材料与方法。这项横断面研究是在甲状腺自身免疫性疾病内分泌诊所进行的，其中193名年龄在18至50岁的妇女患有GD，而66名年龄在18至60岁的妇女患有HT。对这些妇女进行了采访，以获取有关自身免疫性疾病的妇产科史和家族史的数据。他们的病历经过审查以确定该疾病的特征并确认与其他自身免疫性疾病的关联。不孕症定义为未经受保护的性交12个月而未受孕。结果。 GD的不育患病率为52.3％，HT的患病率为47.0％。 GD和HT诊断时的平均年龄分别为36.5岁和39.2岁。在诊断时年龄小于等于35岁的女性中，平均怀孕率较低，并且在诊断出该疾病后，无论年龄大小，其平均妊娠率始终较低。与不育症有关的唯一变量是HT病的病程较短。结论患有GD和HT的女性的不孕症患病率很高，并影响了年轻女性的怀孕次数。

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