...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Epidemiology: Official Journal of the International Epidemiological Association >Long-term mortality amongst Gulf War Veterans: is there a relationship with experiences during deployment and subsequent morbidity?
【24h】

Long-term mortality amongst Gulf War Veterans: is there a relationship with experiences during deployment and subsequent morbidity?

机译：海湾战争退伍军人的长期死亡率：部署和随后的发病率是否与经验有关？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Gulf War Veterans have previously been shown to have, in the short-term, an excess risk of death from 'external' (i.e. non-disease) causes of death. This study aims to determine whether there remains an excess of non-disease-related deaths in Gulf Veterans, 13 years after deployment, and, for the first time, to determine whether there is a relationship between experiences reported in the Gulf, post-war symptoms, and subsequent mortality experience. METHODS: We conducted a cohort study with follow-up from April 1, 1991 (the end of the Gulf War) to June 30, 2004. Participants were 53 462 Gulf War Veterans and a cohort of military personnel, matched for age-group, sex, rank, service and level of fitness, who were not deployed to the Gulf. The outcome measure used was mortality as recorded on the NHS central register. RESULTS: There is no difference, 13 years after the end of the Gulf War, in the overall mortality experience of Gulf War Veterans. The excess in non-disease-related deaths previously reported is confined to the initial 7 years of follow-up [mortality rate ratio (MRR) 1.31, 95% confidence interval (CI) 1.06-1.63] rather than the more recent period (MRR 1.05, 95% CI 0.83-1.33). Overall experiences reported during Gulf deployment did not influence subsequent risk of dying, but there was non-significant increased risk of dying from a disease-related death (MRR 1.99, 95% CI 0.98-4.04) associated with reported exposure to depleted uranium and of a non-disease-related death associated with reporting handling of pesticides (MRR 2.05, 95% CI 0.91-4.61). Reporting of morbidity in the health surveys conducted was not related to future risk of death. CONCLUSION: The higher rates of non-disease-related deaths in Gulf War Veterans is not evident in the period of follow-up since 1997. Neither the excess morbidity reported in health surveys nor the experiences during deployment significantly influenced future mortality. The two non-significant associations found (reported depleted uranium exposure and disease death, reporting handling pesticides and non-disease deaths) need to be considered in the context of the number of possible associations examined and potential biases-although they are biologically plausible.
机译：背景：以前已经证明，海湾战争退伍军人在短期内有来自“外部”（即非疾病）死亡原因的额外死亡风险。这项研究的目的是确定部署后13年的海湾退伍军人中是否仍存在与非疾病相关的死亡人数，并且首次确定战后海湾地区所报告的经验之间是否存在关联症状和随后的死亡经历。方法：我们从1991年4月1日（海湾战争结束）至2004年6月30日进行了队列研究，参与者为53462海湾战争退伍军人和一组军事人员，按年龄段，尚未部署到海湾地区的性别，职级，服务和健身水平。所使用的结局指标是NHS中央登记册上记录的死亡率。结果：海湾战争结束后13年，海湾战争退伍军人的整体死亡率没有差异。先前报道的与非疾病相关的死亡人数过多，仅限于随访的最初7年[死亡率（MRR）1.31，95％置信区间（CI）1.06-1.63]，而不是最近时期（MRR） 1.05，95％CI 0.83-1.33）。据报道，在海湾部署期间的总体经验并未影响随后的死亡风险，但与报告的贫铀暴露和与之相关的疾病相关死亡（MRR 1.99，95％CI 0.98-4.04）的死亡风险没有显着增加。与报告农药处理相关的非疾病相关死亡（MRR 2.05，95％CI 0.91-4.61）。在进行的健康调查中，发病率的报告与将来的死亡风险无关。结论：自1997年以来的随访期间，海湾战争退伍军人中与非疾病相关的死亡率较高并不明显。健康调查中报告的高发病率和部署期间的经验均未显着影响未来的死亡率。尽管存在生物学上的合理联系，但仍应考虑两个被发现的非重要协会（报告的贫铀暴露和疾病死亡，报告处理杀虫剂和非疾病死亡），并检查可能存在的协会数量和潜在偏见。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号