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首页> 外文期刊>British journal of ophthalmology >Risk of non-arteritic anterior ischaemic optic neuropathy (NAION) after cataract extraction in the fellow eye of patients with prior unilateral NAION.
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Risk of non-arteritic anterior ischaemic optic neuropathy (NAION) after cataract extraction in the fellow eye of patients with prior unilateral NAION.

机译：白内障摘除术后既往单侧NAION患者的另一只眼睛发生非动脉性前部缺血性视神经病变（NAION）的风险。

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摘要

AIM: To determine the risk of non-arteritic anterior ischaemic optic neuropathy (NAION) after cataract extraction (CE) in the fellow eye of patients with prior unilateral NAION. DESIGN: Retrospective, cohort study. METHODS: Medical records of patients with NAION evaluated in our institution between 1 January 1986 and 31 December 2001 were reviewed to determine the onset of NAION and the time of CE. Patients were excluded if the date of NAION and CE was unreliable, or if CE in the fellow eye was performed before the unilateral NAION. Statistical analysis was performed by including fellow eye CE as a time-dependent covariate in a Cox proportional hazards regression model of NAION incidence in the fellow eye. RESULTS: Of the 325 eligible patients, 9 (53%) of 17 patients with NAION who underwent CE in the fellow eye developed fellow eye NAION, and 59 (19%) of 308 patients with NAION who did not undergo CE in the fellow eye developed fellow eye NAION. Cataract extraction in the fellow eye increased the riskof NAION occurrence in the fellow eye by 3.6-fold (Cox regression, p=0.001). CONCLUSIONS: Patients with unilateral NAION are at a significantly higher risk of developing NAION in the fellow eye after CE.
机译：目的：确定患有单侧NAION的患者的另一只眼在白内障摘除（CE）后非动脉性前部缺血性视神经病变（NAION）的风险。设计：回顾性队列研究。方法：回顾了1986年1月1日至2001年12月31日在本机构评估的NAION患者的病历，以确定NAION的发病时间和CE发生时间。如果NAION和CE的日期不可靠，或者同侧眼睛的CE在单侧NAION之前进行，则排除患者。通过将同眼CE作为随时间的协变量包括在同眼NAION发生率的Cox比例风险回归模型中进行统计分析。结果：在325名合格患者中，在同眼中接受CE的17例NAION患者中有9例（53％）发展为同眼NAION，在308例NAION患者中有59例（19％）未经历CE发达的眼神NAION。在另一只眼中摘除白内障会使在另一只眼中出现NAION的风险增加3.6倍（Cox回归，p = 0.001）。结论：CE后单眼NAION患者在另一只眼中发展NAION的风险明显更高。

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