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The stress on the anterior lens surface during human in vivo accommodation.

机译:人体体内适应过程中前镜片表面的应力。

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PURPOSE: To determine the qualitative change in stress on the lens capsule during in vivo human accommodation. METHODS: Nine subjects (mean age: 30 years; range: 25-38 years) were studied, each of whom had undergone a phakic refractive intraocular lens (PRL) surgical procedure. The change, during accommodation, of stress on the surface of the anterior lens capsule (ALS) was determined by employing high-resolution anterior segment optical coherence tomography (OCT). This was done by comparing the ratio of the intensity of the image from the anterior surface of the natural lens (ALS) to the images of the anterior corneal surface (ACS), posterior corneal surface (PCS) and the posterior surface of the phakic refractive intraocular lens (PPRLS) before and during accommodation. RESULTS: The intensities of the OCT images of the ACS and PPRLS did not significantly change during accommodation when compared with their respective baselines, while the intensity ratios: ALS/ACS, ALS/PCS and ALS/PPRLS all significantly increased during accommodation (p<0.01). CONCLUSIONS: The stress on the anterior lens capsule is increased during in vivo human accommodation. This observation is consistent with a mechanism of accommodation in which zonular tension increases with accommodation, which is opposite to the predictions of the Helmholtz theory.
机译:目的:确定在体内人类适应过程中晶状体囊的应力的质的变化。方法:对9名受试者(平均年龄:30岁;范围:25-38岁)进行了研究,每位受试者均接受了有晶状体屈光人工晶状体(PRL)手术。在适应过程中,通过采用高分辨率前节光学相干断层扫描(OCT)确定前晶状体囊(ALS)表面应力的变化。通过比较来自自然晶状体前表面(ALS)的图像强度与角膜前表面(ACS),角膜后表面(PCS)和有晶状体屈光后表面的图像强度的比值来完成此操作调节前后的人工晶状体(PPRLS)。结果:ACS和PPRLS的OCT图像强度在适应过程中与各自的基线相比没有显着变化,而强度比:ALS / ACS,ALS / PCS和ALS / PPRLS在适应过程中均显着增加(p < 0.01)。结论:在体内人体适应过程中,前晶状体囊的应力增加。该观察结果与调节机制一致,在该调节机制中,纬向张力随调节而增加,这与亥姆霍兹理论的预测相反。

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