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首页> 外文期刊>International journal of hyperthermia: The official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group >Simulation studies promote technological development of radiofrequency phased array hyperthermia. 1996.
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Simulation studies promote technological development of radiofrequency phased array hyperthermia. 1996.

机译:仿真研究促进了射频相控阵热疗技术的发展。 1996年。

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摘要

A treatment planning program package for radiofrequency hyperthermia has been developed. It consists of software modules for processing three-dimensional computerized tomography (CT) data sets, manual segmentation, generation of tetrahedral grids, numerical calculation and optimisation of three-dimensional E field distributions using a volume surface integral equation algorithm as well as temperature distributions using an adaptive multilevel finite-elements code, and graphical tools for simultaneous representation of CT data and simulation results. Heat treatments are limited by hot spots in healthy tissues caused by E field maxima at electrical interfaces (bone/muscle). In order to reduce or avoid hot spots suitable objective functions are derived from power deposition patterns and temperature distributions, and are utilised to optimise antenna parameters (phases, amplitudes). The simulation and optimisation tools have been applied to estimate the improvements that could be reached by upgrades of the clinically used SIGMA-60 applicator (consisting of a single ring of four antenna pairs). The investigated upgrades are increased number of antennas and channels (triple-ring of 3 x 8 antennas and variation of antenna inclination. Significant improvement of index temperatures (1-2degC) is achieved by upgrading the single ring to a triple ring with free phase selection for every antenna or antenna pair. Antenna amplitudes and inclinations proved as less important parameters.
机译:已经开发了用于射频热疗的治疗计划程序包。它包括用于处理三维计算机断层扫描(CT)数据集,手动分割,生成四面体网格,使用体积表面积分方程算法进行三维E场分布的数值计算和优化以及使用ABS进行温度分布的软件模块自适应多级有限元代码,以及用于同时表示CT数据和仿真结果的图形工具。热处理受限于健康组织中由电接口(骨骼/肌肉)处的电场最大值引起的热点。为了减少或避免热点,从功率沉积图案和温度分布导出合适的目标函数,并将其用于优化天线参数(相位,幅度)。仿真和优化工具已用于评估临床使用的SIGMA-60辐射器(由四个天线对组成的单个环)的升级所能达到的改进。所研究的升级是增加天线和信道的数量(3 x 8天线的三环和天线倾斜度的变化。通过将单环升级为具有自由相位选择的三环,可以显着改善指标温度(1-2degC)对于每个天线或天线对,天线幅度和倾斜度被认为是次要的参数。

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