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首页> 外文期刊>International journal of hyperthermia: The official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group >Design of a water coupling bolus with improved flow distribution for multi-element superficial hyperthermia applicators.
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Design of a water coupling bolus with improved flow distribution for multi-element superficial hyperthermia applicators.

机译:用于多元素浅表热疗器的水流分配器具有改进的流量分配设计。

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摘要

A water bolus used in superficial hyperthermia couples the electromagnetic (EM) or acoustic energy into the target tissue and cools the tissue surface to minimise thermal hotspots and patient discomfort during treatment. Parametric analyses of the fluid pressure inside the bolus computed using 3D fluid dynamics simulations are used in this study to determine a bolus design with improved flow and surface temperature distributions for large area superficial heat applicators. The simulation results are used in the design and fabrication of a 19 x 32 cm prototype bolus with dual input-dual output (DIDO) flow channels. Sequential thermal images of the bolus surface temperature recorded for a step change in the circulating water temperature are used to assess steady state flow and surface temperature distributions across the bolus. Modelling and measurement data indicate substantial improvement in bolus flow and surface temperature distributions when changing from the previous single input-single output (SISO) to DIDO configuration. Temperature variation across the bolus at steady state was measured to be less than 0.8 degrees C for the DIDO bolus compared to 1.5 degrees C for the SISO water bolus. The new DIDO bolus configuration maintains a nearly uniform flow distribution and low variation in surface temperature over a large area typically treated in superficial hyperthermia.
机译:在浅层热疗中使用的水团将电磁(EM)或声能耦合到目标组织,并冷却组织表面,以最大程度地减少治疗期间的热斑和患者不适感。本研究中使用3D流体动力学模拟对弹丸内部的流体压力进行参数分析,以确定用于大面积表面加热器的弹丸设计,该弹丸设计具有改善的流量和表面温度分布。仿真结果用于设计和制造具有双输入双输出(DIDO)流道的19 x 32 cm原型推注。针对循环水温度的阶跃变化记录的大剂量表面温度的连续热图像用于评估稳态流量和整个大剂量表面的温度分布。建模和测量数据表明,当从先前的单输入单输出(SISO)更改为DIDO配置时,推注流量和表面温度分布将得到显着改善。对于DIDO推注,稳态时整个推注的温度变化均测得小于0.8摄氏度,而SISO水推注则为1.5摄氏度。新的DIDO推注配置可在通常经表面热疗治疗的大面积区域内保持几乎均匀的流量分布和较低的表面温度变化。

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