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Depression in informal caregivers of persons with dementia

机译:痴呆症患者的非正式照护者的抑郁

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Background: Worldwide, there are more than 35 million individuals diagnosed with Alzheimer's disease. Many of these individuals are cared for at home by unpaid caregivers who often report high levels of depressive symptoms and depression. The majority of studies conducted to predict which caregivers are at risk for depression have examined non-modifiable risk factors. Therefore, it is important to discover modifiable factors that may be associated with risk for depression in caregivers. Objectives: The aims of this research were to identify a set of factors that are modifiable and known to be associated with high levels of depression/depressive symptomology (D/DS) in other populations and to determine whether these factors are predictive of D/DS after controlling for non-modifiable, demographic, and clinical factors. Design: Secondary data analysis. Methods: Fifty-three participants provided direct care to a person with dementia with night-time activity. Inclusion criteria included not undergoing treatment for sleep disorders; living with the care recipient; and a Mini-Mental Status Exam score > 27. Baseline data collected by questionnaires, sleep diary and actigraphy. Results: In multivariate analyses of the modifiable factors, only high levels of negative affect predicted higher levels of depressive symptomatology. When non-modifiable factors were included in the model, negative affect and high levels of perceived caregiver burden predicted 52.6% of the variance in depressive symptomology. In secondary analyses, wake after sleep onset misperception was associated with higher depression scores. Conclusions: While negative affect had a moderate effect on depressive symptoms, modifiable factors often associated with depressive symptoms in other studies were not associated with caregiver depression in this study. Possibly caregivers' overall poor sleep causes a floor effect and masks a potential relationship. Implications for practice: Both caregivers' affect and perceived burden are strongly related to depressive symptoms, so healthcare practitioners need to frequently assess both so as to provide timely interventions.
机译:背景:在全球范围内,有超过3500万被诊断患有阿尔茨海默氏病的人。这些人中有许多人在家中由无报酬的看护人照料,他们通常会报告高水平的抑郁症状和抑郁症。为预测哪些护理员有患抑郁症的风险而进行的大多数研究都检查了不可改变的危险因素。因此,重要的是发现可能与看护者抑郁风险相关的可调节因素。目的:这项研究的目的是确定一组可以改变的,已知与其他人群中高水平的抑郁/抑郁症状(D / DS)相关的因素,并确定这些因素是否可预测D / DS在控制了不可修改的人口统计学和临床​​因素之后。设计:辅助数据分析。方法:53名参与者通过夜间活动为痴呆症患者提供直接护理。纳入标准包括不接受睡眠障碍治疗;与被护理人住在一起;以及迷你精神状态检查分数>27。通过问卷,睡眠日记和书法记录收集的基线数据。结果:在可改变因素的多元分析中,只有高水平的负面影响才能预测较高水平的抑郁症症状。当模型中包含不可修改的因素时,负面影响和较高的看护者负担预测了抑郁症状的变化的52.6%。在二级分析中,入睡后觉醒后的误解与较高的抑郁评分有关。结论:虽然负面影响对抑郁症状有中等程度的影响,但在其他研究中通常与抑郁症状相关的可改变因素在本研究中与护理者抑郁无关。可能是护理人员的整体睡眠不足会导致地板不适并掩盖潜在的关系。对实践的影响:护理人员的影响和感知负担都与抑郁症状密切相关,因此医疗保健从业人员需要经常评估两者,以便及时提供干预措施。

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