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首页> 外文期刊>International journal of pediatric otorhinolaryngology >Mandibular distraction osteogenesis in children with Pierre Robin sequence: Impact on health-related quality of life
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Mandibular distraction osteogenesis in children with Pierre Robin sequence: Impact on health-related quality of life

机译：皮埃尔·罗宾（Pierre Robin）序列患儿的下颌骨分散性成骨：对健康相关生活质量的影响

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Background: Upper airway obstruction in children with Pierre Robin sequence (PRS) may be severe enough to require surgical intervention. Although many studies have demonstrated the effectiveness of mandibular distraction osteogenesis (MDO) in relieving airway obstruction, no study has reported health-related quality of life (QOL) outcomes.The objective of the present study was to conduct the first health-related QOL assessment post-MDO. Methods: The Glasgow Children's Benefit Inventory (GCBI) questionnaire was distributed in a retrospective manner to the caregivers of all children who had undergone MDO at the authors' institutions between January 2007 and December 2010. Patients who had other major surgical procedures were excluded. Results: The response rate was 84% (21 of 25 questionnaires completed). The total mean GCBI score was +54 (SD, 19.5), which demonstrated a subjective overall benefit in health-related QOL post-MDO. All of the domains within the GCBI also scored in the positive range, indicating domain specific improvements in health-related QOL. There were no significant differences in the GCBI scores between syndromic-PRS patients and isolated PRS patients; similar results were observed between tracheostomy patients and no tracheostomy patients. Summary: In treating children with PRS and severe upper airway obstruction, MDO resulted in a subjective overall benefit in health-related QOL in our study population.
机译：背景：皮埃尔·罗宾序列（PRS）患儿的上呼吸道阻塞可能严重到需要手术干预。尽管许多研究表明下颌骨牵引成骨（MDO）可以缓解气道阻塞，但尚无研究报告健康相关的生活质量（QOL）结果。本研究的目的是进行首次健康相关的QOL评估MDO后。方法：以回顾性方式向格拉斯哥儿童福利调查表（GCBI）分发给所有在2007年1月至2010年12月间在作者机构接受MDO治疗的儿童的照料者。排除了其他主要手术方法的患者。结果：答复率为84％（已完成25份问卷中的21份）。 GCBI总平均得分为+54（标准差，19.5），这表明在MDO后与健康相关的QOL中，主观总体获益。 GCBI内的所有领域也都在正值范围内，表明与健康相关的QOL在领域方面有所改善。有症状的PRS患者和孤立的PRS患者之间的GCBI评分没有显着差异。在气管切开术患者和无气管切开术患者之间观察到相似的结果。摘要：在治疗患有PRS和严重上呼吸道阻塞的儿童时，MDO在我们研究的人群中对健康相关的QOL产生了主观的总体益处。

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