SCANNING ION MICROBEAM ANALYSIS OF DIFFUSION IN IN-MOUTH DRUG RELEASE POLYMERS

G. Massingham; R. Arslanoglu; F. E. Gauntlett; M. S. Rihawy; R. W. Smith; A. S. Clough; M. Braden; M. P. Patel

首页> 外文期刊>International journal of PIXE >SCANNING ION MICROBEAM ANALYSIS OF DIFFUSION IN IN-MOUTH DRUG RELEASE POLYMERS

【24h】

SCANNING ION MICROBEAM ANALYSIS OF DIFFUSION IN IN-MOUTH DRUG RELEASE POLYMERS

机译：口内药物释放聚合物扩散的扫描离子微束分析

获取原文

获取原文并翻译 | 示例

获取外文期刊封面封底 >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

With the aim of characterizing polymer-based drug delivery systems a combination of Scanning MeV 3He microbeam Nuclear Reaction, Backscattering and Particle Induced X-ray Emission (PIXE) techniques has been developed. This, together with gravimetric and UV techniques has been applied to characterize both water infusion and drug effusion for three in-mouth polymer–drug systems. Preliminary results are presented from the exposure of polymers, containing drug at a level of 9% by weight of the dry polymer, to both pure water and a phosphate buffered saline solution at 37°C.

机译：为了表征基于聚合物的药物递送系统，已经开发了扫描MeV 3He微束核反应，反向散射和粒子诱导X射线发射（PIXE）技术的组合。这与重量分析和紫外线技术一起已被用于表征三种口内聚合物-药物系统的水注入和药物渗出。初步结果是在37℃下将含有药物的聚合物（按干燥聚合物的重量计为9％）暴露于纯水和磷酸盐缓冲盐溶液中。

著录项

来源
《International journal of PIXE》 |2005年第4期|共7页
作者
G. Massingham; R. Arslanoglu; F. E. Gauntlett; M. S. Rihawy; R. W. Smith; A. S. Clough; M. Braden; M. P. Patel;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类 X射线;
关键词
Polymers; controlled drug delivery; water diffusion; ion beam analysis;

机译：聚合物;可控药物输送;水扩散;离子束分析;

相似文献

外文文献
中文文献
专利

1. SCANNING ION MICROBEAM ANALYSIS OF DIFFUSION IN IN-MOUTH DRUG RELEASE POLYMERS [J] . G. Massingham, R. Arslanoglu, F. E. Gauntlett, International journal of PIXE . 2005,第3a4期

机译：口内药物释放聚合物扩散的扫描离子微束分析
2. Finite element analysis of diffusional drug release from complex matrix systems. II. Factors influencing release kinetics [J] . Wu XY., Zhou Y. Journal of Controlled Release: Official Journal of the Controlled Release Society . 1998,第1期

机译：复杂基质系统扩散药物释放的有限元分析。 II。影响释放动力学的因素
3. Using a scanning microbeam and a CdZnTe array for nuclear reaction measurements of water diffusion into an adhesive resin [J] . F.E. Gauntlett, M.S. Rihawy, A.S. Clough, Nuclear Instruments & Methods in Physics Research. B, Beam Interactions with Materials and Atoms . 2006,第Aug期

机译：使用扫描微束和CdZnTe阵列进行核反应测量水扩散到粘合树脂中
4. Controlled Drug Diffusion for Oral Extended Release of Highly Water-soluble Drugs Utilizing their Micelle-forming Property and Counter Polymer [C] . Controlled Release Society annual meeting . 2004

机译：用于口服胶水可溶性药物的受控药物扩散利用其胶束形成性能和抗衡聚合物
5. Analysis and application of bio-erodible swelling polymers in the development of controlled -release matrix systems for low-dose BCS class 2 drugs, using glipizide as a model drug [D] . Jamzad, Shahla 2006

机译：以格列吡嗪为模型药物的生物易蚀溶胀聚合物在低剂量BCS 2类药物控释基质系统开发中的分析和应用
6. Automated laser-scanning-microbeam fluorescence/Raman image analysis of human lens with multichannel detection: evidence for metabolic production of a green fluorophor. [O] . N T Yu, M Z Cai, D J Ho, 1988

机译：具有多通道检测功能的人晶状体的自动激光扫描微束荧光/拉曼图像分析：绿色荧光团代谢产生的证据。
7. Formulation of 3D Printed Tablet for Rapid Drug Release by Fused Deposition Modeling: Screening Polymers for Drug Release, Drug-Polymer Miscibility and Printability [O] . Nayan G. Solanki, Md Tahsin, Ankita V. Shah, 2018

机译：用熔融沉积建模的快速药物释放3D印刷片剂：用于药物释放的筛选聚合物，药物 - 聚合物混溶性和可印刷性

SCANNING ION MICROBEAM ANALYSIS OF DIFFUSION IN IN-MOUTH DRUG RELEASE POLYMERS

摘要

著录项

相似文献

相关主题

期刊订阅