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首页> 外文期刊>International journal of PIXE >MEASUREMENT OF TRACE METALS IN THYROID NODULES IN IRAN BY PIXE
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MEASUREMENT OF TRACE METALS IN THYROID NODULES IN IRAN BY PIXE

机译:像素法测定伊朗甲状腺结节中的微量金属

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摘要

A PIXE (Proton Induced X-ray Emission) analysis is applied for measuring the concentration of 21 major and minor trace metal elements (in the range of Z=13-53) for normal, adenoma and carcinoma human thyroid tissues. A 2.0 MeV proton beam was employed to excite the samples. The thyroid samples were obtained from 14 patients during surgical operations, with which normal and damaged parts are concerned as an aid to understand the mechanisms of formation of thyroid cancer and as a complementary diagnostic tool. Thirty samples were measured in total. Fourteen samples of them were in pairs, i.e.14 tumor samples with 14 corresponding healthy tissue specimens taken at a distance from the tumor. The statistical analysis of the results shows the lower levels of the mean value of iron and iodine in the carcinoma tissues than those in the normal tissues; especially iodine is about one tenth of the normal value. On the contrary, the elevation of the mean value for calcium and zinc in the carcinoma tissues in comparison with the normal ones is observed, while in the adenoma tissues copper is very lower than those in the normal thyroid. The concentration of iron in the adenoma is two times of normal tissues.
机译:PIXE(质子诱导的X射线发射)分析用于测量正常,腺瘤和人类甲状腺癌组织中21种主要和次要微量金属元素(在Z = 13-53范围内)的浓度。使用2.0 MeV质子束激发样品。甲状腺样品是在手术过程中从14例患者中获得的,与之相关的正常部分和受损部分有助于了解甲状腺癌的形成机理并作为辅助诊断工具。总共测量了30个样品。它们中的14个样品成对存在,即14个肿瘤样品和14个相应的健康组织标本,距离肿瘤一定距离。结果的统计分析表明,癌组织中铁和碘的平均值低于正常组织中的平均值。尤其是碘,大约是正常值的十分之一。相反,观察到癌组织中钙和锌的平均值与正常组织相比升高,而在腺瘤组织中,铜的含量远低于正常甲状腺。腺瘤中铁的浓度是正常组织的两倍。

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