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首页> 外文期刊>American journal of medical genetics, Part A >Genetic counseling for teratogenic risk due to exposure to medications: 89 pregnancies conceived during oral contraceptive use.
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Genetic counseling for teratogenic risk due to exposure to medications: 89 pregnancies conceived during oral contraceptive use.

机译：因接触药物致畸风险的遗传咨询：口服避孕药期间怀孕89次。

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摘要

Congenital malformations are relatively frequent (2% of the general population) but only a small proportion of them can be ascribed to medication exposure during pregnancy [Polifka and Friedman, 2002]. Nevertheless, for the purposes of accurate prenatal diagnosis, monitoring and research, is it important to offer teratology counseling to patients exposed to drugs [Hancock et al., 2007]. There are approximately 20 medications currently on the market that have been universally acknowledged as teratogenic (Table I) [Webster and Freeman, 2001 ]. At the current state of the art, exposure of early embryos to oral contraceptives is not considered teratogenic [Bracken, 1990].
机译：先天性畸形相对频繁（占总人口的2％），但其中只有一小部分可归因于怀孕期间的药物暴露[Polifka and Friedman，2002]。然而，出于精确的产前诊断，监测和研究的目的，向接触药物的患者提供畸形咨询是很重要的[Hancock et al。，2007]。目前市场上大约有20种药物被普遍认为具有致畸性（表I）[Webster and Freeman，2001]。在目前的技术水平下，早期胚胎暴露于口服避孕药不被认为具有致畸性[Bracken，1990]。

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