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首页> 外文期刊>International Journal of Radiation Oncology, Biology, Physics >Factors associated with the frequency of self-intermittent catheterization after prostate brachytherapy.
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Factors associated with the frequency of self-intermittent catheterization after prostate brachytherapy.

机译：与前列腺近距离放射治疗后自我间歇导尿频率相关的因素。

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摘要

PURPOSE: Urinary obstructive symptoms are the most common side effects of transperineal interstitial permanent prostate brachytherapy (TIPPB). Self-intermittent catheterization (SIC) can be used to relieve urinary retention. This study evaluated the factors associated with the probability of a patient performing SIC after TIPPB. METHODS AND MATERIALS: We prospectively evaluated 204 patients who underwent TIPPB at Mayo Clinic Scottsdale (MCS). All patients were taught to perform SIC before implant and were instructed to do so if they could not urinate at any time after the procedure. RESULTS: Of the 204 patients, 22 patients (11%) received (103)Pd seeds and 182 patients (89%) received (125)I. Thirty-seven (18%) patients received external-beam radiotherapy (XRT) in addition to the TIPPB. SIC was performed by 69 (34%) of the 204 patients. Factors that were significantly associated with a lower frequency of SIC were prostate volumes < or = 34.2 cm(3) (p = 0.005), < or = 137 seeds implanted (p = 0.04), prostate-specific antigen (PSA) levels < or = 6.35 (p = 0.03), American Urological Association (AUA) score < or = 10 (p = 0.01), the use of (125)I (p = 0.03), and the addition of XRT to the implant (p = 0.02). CONCLUSIONS: Significant associations were observed between the frequency of SIC and the number of seeds implanted, AUA scores, prostate volume, PSA levels, addition of XRT, and isotope used. Whereas the first four of these factors may be surrogates for prostate volume and obstructive symptoms in general, the last two factors are related to treatment decisions. These findings may aid in better patient selection and therapeutic decisions. Additionally, this information may provide a clearer understanding of the urinary side effects of TIBBP.
机译：目的：尿路阻塞症状是经会阴间质性永久性前列腺近距离放射疗法（TIPPB）的最常见副作用。自间断导尿（SIC）可用于缓解尿retention留。这项研究评估了与TIPPB后患者进行SIC的可能性相关的因素。方法和材料：我们前瞻性地评估了204位在梅奥诊所斯科茨代尔（MCS）接受TIPPB治疗的患者。教导所有患者在植入前进行SIC，并指导他们在手术后任何时候都不能排尿。结果：204例患者中，22例（11％）接受了（103）Pd种子，182例患者（89％）接受了（125）I。除TIPPB外，三十七（18％）位患者接受了体外放射治疗（XRT）。 204位患者中有69位（34％）进行了SIC。与SIC发生频率降低显着相关的因素是前列腺体积<或= 34.2 cm（3）（p = 0.005），<或=植入了137颗种子（p = 0.04），前列腺特异性抗原（PSA）水平<或= 6.35（p = 0.03），美国泌尿外科协会（AUA）得分<或= 10（p = 0.01），使用（125）I（p = 0.03）以及在植入物中添加XRT（p = 0.02） ）。结论：观察到SIC的频率与植入种子的数量，AUA评分，前列腺体积，PSA水平，XRT的添加和所使用的同位素之间存在显着相关性。通常，这些因素中的前四个因素可能是前列腺体积和阻塞性症状的替代物，而后两个因素与治疗决策有关。这些发现可能有助于更好的患者选择和治疗决策。此外，此信息可以使您更清楚地了解TIBBP的尿毒副作用。

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