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Influence of exercise mode and carbohydrate on the immune response to prolonged exercise.

机译:运动方式和碳水化合物对长时间运动的免疫反应的影响。

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The influence of exercise mode and 6% carbohydrate (C) versus placebo (P) beverage ingestion on lymphocyte proliferation, natural killer cell cytotoxicity (NKCA), Interleukin (IL)-1beta production, and hormonal responses to 2.5 hr of intense running and cycling (approximately 75% VO2max) was measured in 10 triathletes serving as their own controls. The C versus P condition (but not exercise mode) resulted in higher plasma glucose concentrations, lower plasma cortisol concentrations, reduced postexercise lymphocytosis and NKCA, and a lessened T-cell reduction during recovery, No condition or mode effects were observed for concanavalin A and phytohemagglutinin-induced lymphocyte proliferation. Significant mode (but not condition) effects were observed for lipopolysaccharide-induced IL-1beta production over time. However, when expressed per monocyte, the mode effect was abolished and a sustained suppression in IL-1beta/monocyte was observed in all sessions throughout recovery. These data indicate that carbohydrate ingestion significantly affects plasma glucose and cortisol concentrations, blood lymphocyte counts, and NKCA, whereas exercise mode has no effect on these parameters.
机译:运动方式和6%碳水化合物(C)与安慰剂(P)饮料摄入对淋巴细胞增殖,自然杀伤细胞细胞毒性(NKCA),白细胞介素(IL)-1beta产生以及对2.5小时剧烈跑步和骑自行车的激素反应的影响在作为自己的对照的10位铁人三项运动员中测量了(最大VO2max约为75%)。 C对P状态(而非运动模式)导致血浆葡萄糖浓度升高,血浆皮质醇浓度降低,运动后淋巴细胞增多和NKCA降低,以及恢复期间T细胞的减少程度降低。伴刀豆球蛋白A和植物血凝素诱导的淋巴细胞增殖。随着时间的推移,观察到脂多糖诱导的IL-1β产生的显着模式(但无条件)效应。然而,当以单核细胞表达时,模式效应被消除,并且在整个恢复过程的所有阶段中均观察到IL-1beta /单核细胞的持续抑制。这些数据表明,碳水化合物的摄入显着影响血浆葡萄糖和皮质醇浓度,血液淋巴细胞计数和NKCA,而运动方式对这些参数没有影响。

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