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首页> 外文期刊>International journal of sports medicine >The impact of acute gastroenteritis on haematological markers used for the athletes biological passport - report of 5 cases.
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The impact of acute gastroenteritis on haematological markers used for the athletes biological passport - report of 5 cases.

机译：急性胃肠炎对运动员生物护照所用血液学指标的影响-附5例报告。

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摘要

The haematological module of the "Athletes Biological Passport" (ABP) is used to detect blood doping through the longitudinal variation of blood variables, such as haemoglobin concentration (Hb). Sporting federations have opened disciplinary procedures against athletes based on ABP results. Suspicious athletes try to explain the variations in their blood values with dehydration caused by gastrointestinal (GI) problems. The aim of the present report is to describe haemoglobin concentration, a key variable of the ABP, during acute gastroenteritis in athletes. 5 athletes with severe gastroenteritis were studied in retrospective. Blood test results (Hb, white blood cell count (WBC) and differential, CRP) obtained on hospital admission for GI problems were compared to data obtained from the same athletes in states of good health on previous occasions. During GI problems, athletes displayed marked inflammatory constellations with increased CRP and typical WBC shifts. Hb was not affected and remained mostly unchanged. This is in line with basic physiologic fluid regulation, where plasma volume is kept constant, even under conditions of severe dehydration. It is therefore unlikely that fluid loss associated with gastroenteritis will cause athletes blood data to reach levels of abnormality that will be suspicious of blood doping.
机译：“运动员生物护照”（ABP）的血液学模块用于通过血液变量（如血红蛋白浓度（Hb））的纵向变化来检测血液中的兴奋剂。体育联合会已根据ABP结果对运动员开放了纪律处分程序。可疑的运动员试图解释由于胃肠道（GI）问题引起的脱水导致的血液价值变化。本报告的目的是描述运动员急性胃肠炎期间的血红蛋白浓度（ABP的关键变量）。回顾性研究了5名严重胃肠炎运动员。将入院时因胃肠道问题而获得的血液测试结果（血红蛋白，白细胞计数（WBC）和差异，CRP）与以前几次健康状况相同的运动员的数据进行比较。在胃肠道问题期间，运动员表现出明显的炎症构象，伴有CRP增加和典型的WBC移位。血红蛋白没有受到影响，基本上保持不变。这与基本的生理液调节相一致，即使在严重脱水的情况下，血浆体积也保持恒定。因此，与胃肠炎有关的体液流失不太可能使运动员的血液数据达到异常水平，这种异常水平可能会引起血液掺杂。

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