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首页> 外文期刊>British journal of neurosurgery >Survival and regeneration of deep-freeze preserved autologous cranial bones after cranioplasty
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Survival and regeneration of deep-freeze preserved autologous cranial bones after cranioplasty

机译：颅骨成形术后深冻保存的自体颅骨的存活和再生

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Background. After decompressive craniectomy, a deep-freeze-preserved autologous cranial bone graft can be used for cranioplasty to avoid immunoreaction against an artificial patch material. Autologous cranial bone grafts not only have better physical properties, such as heat conduction, compared to artificial patch materials, but they also have the advantages of a lower medical cost and satisfactory physical flexibility. The discussion over 99Tc m-MDP SPECT static cranial bone tomography in the diagnosis of survival and regeneration in deep-freeze preservation autologous cranial bones after cranioplasty is valuable. Objective. To investigate whether deep-freeze-preserved autologous cranial bone grafts could survive and regenerate after autologous reimplantation. Methods. The method of cranial bone preservation involved removing the cranial graft and sealing it in a double-layer sterile plastic bag under sterile surgical conditions. On the day of the cranioplasty operation, the cranial bone graft was disinfected by immersing it in 3% povidoneiodine for 30 minutes. At short-term (2 weeks), medium-term (3 months), and long-term (12 months) postoperative follow-up visits, 99Tc m-MDP SPECT static cranial bone tomography was used to examine the reimplanted cranial bone. Results. There were no postoperative infections or seromas in all 16 cases. Two weeks following cranial bone graft reimplantation, the SPECT tomography showed some radioactivity uptake in the reimplanted cranial bone graft, which was lower than that in the cranial bone on the healthy side. At 3 months and 12 months after the operation, the radioactivity uptake in the reimplanted cranial bone graft was the same as that in the cranial bone on the healthy side. X-ray films showed blurred sutures in the reimplanted cranial bone graft at 12 months after surgery. Conclusion. Reimplanted deep-freeze-preserved autologous cranial bone can survive in the short term and regenerate in the medium and long terms.
机译：背景。减压颅骨切除术后，可以将保留深冻的自体颅骨移植物用于颅骨成形术，以避免对人工贴片材料的免疫反应。与人工贴片材料相比，自体颅骨移植物不仅具有更好的物理性能，例如导热性，而且还具有降低医疗成本和令人满意的物理柔韧性的优点。 99Tc m-MDP SPECT静态颅骨层析成像在颅骨成形术后深冻保存自体颅骨的存活和再生诊断中的讨论是有价值的。目的。研究深冷冻保存的自体颅骨移植物能否在自体再植后存活并再生。方法。保存颅骨的方法包括取出颅骨移植物，并在无菌手术条件下将其密封在双层无菌塑料袋中。在颅骨手术当天，将颅骨移植物浸入3％聚维酮碘中30分钟，以对其进行消毒。在术后短期（2周），中期（3个月）和长期（12个月）随访时，使用99Tc m-MDP SPECT静态颅骨断层显像技术检查重新植入的颅骨。结果。 16例均无术后感染或血清肿。颅骨植骨再植入后两周，SPECT断层扫描显示，颅骨植骨中有一些放射性吸收，低于健康侧颅骨的放射性吸收。术后3个月和12个月，再植入颅骨移植物中的放射性吸收与健康侧颅骨中的放射性吸收相同。 X射线胶片显示在术后12个月时再植入的颅骨移植物中缝线模糊。结论。再植入的深冻保存的自体颅骨可以在短期内存活，并在中长期内再生。

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