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首页> 外文期刊>Applied Magnetic Resonance >Multi-level Assessment Cerebrospinal Fluid Flow in Patients with Chiari I Malformation
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Multi-level Assessment Cerebrospinal Fluid Flow in Patients with Chiari I Malformation

机译：Chiari I畸形患者多水平评估脑脊液流量

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摘要

The purpose of this study is to characterize the cerebrospinal fluid (CSF) flow throughout the cardiac cycle in the conditions of Chiari I at intracranial and cervical levels. Magnetic resonance imaging studies were examined with phasecontrast magnetic resonance imaging retrospectively cardiac triggered (Quantitative Flow technique). 60 healthy volunteers (control group) and 12 patients with the anomaly of Chiari I (patient's group) were investigated. Mean velocity, mean flux and peak velocity values of CSF flow at the five levels (the Sylvian aqueduct, the fourth ventricle, the Magendie's foramen, subarachnoid space of the foramen occipital magnum and the cervical level) were defined. Analysis of differences between respective mean values of CSF flow has shown that CSF flow characteristics have the highest values in the Sylvian aqueduct and on the cervical level in both groups. Our findings show that mean velocity and mean flux of antegrade (from head to feet) flow have significantly higher values in comparison with the retrograde flow (from feet to head) through investigated structures, respectively (p<0.01). Our findings show the importance of multi-level cerebrospinal fluid flow assessment and allow investigating this system as a single whole, with their relationships and interaction laws.
机译：这项研究的目的是表征在Chiari I情况下颅内和宫颈水平下整个心动周期的脑脊液（CSF）流量。回顾性地通过心脏触发（定量流技术）对相衬磁共振成像检查了磁共振成像研究。调查了60名健康志愿者（对照组）和12例Chiari I异常患者（患者组）。定义了五个水平（Sylvian导水管，第四脑室，Magendie的孔，蛛网膜枕枕大蛛网膜下腔和宫颈水平）五个水平的CSF流速的平均速度，平均通量和峰值速度值。对脑脊液流量平均值之间差异的分析表明，两组的脑脊液流量特性在西尔维亚输水管道和宫颈水平上最高。我们的发现表明，与通过研究结构的逆流（从脚到头）相比，顺流（从头到脚）的平均速度和平均通量分别具有更高的值（p <0.01）。我们的发现表明了多级脑脊髓液流量评估的重要性，并允许将其与关系和相互作用规律作为一个整体进行研究。

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