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首页> 外文期刊>Applied Magnetic Resonance >Effectiveness Evaluation of the Fat Percentage Determination in Multi-Echo T2-Corrected Single-Voxel Spectroscopy by Comparing the 3-Point Dixon and the 6-Point Interference Dixon Techniques
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Effectiveness Evaluation of the Fat Percentage Determination in Multi-Echo T2-Corrected Single-Voxel Spectroscopy by Comparing the 3-Point Dixon and the 6-Point Interference Dixon Techniques

机译：比较三点狄克逊和六点干涉狄克逊技术测定多回波T2校正单体素光谱中脂肪百分比的有效性

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摘要

This study compared fat percentage in the HISTO method and chemical-shift imaging method, a 3-echo 3D gradient echo sequence with a T2*-corrected Dixon (3-point Dixon) and 6-echo interference Dixon magnetic resonance (MR) imaging (6-point Dixon) method, to evaluate clinical significance of fatty liver quantification by multi-echo T2*-corrected single-voxel spectroscopy Histo (HISTO). A total of 21 liver donors underwent MR imaging examination. The 3-T MR system (Siemens Healthcare Tim Verio, Erlangen, Germany) was used for all studies. For fat percentage evaluations, a 3-echo 3D gradient echo sequence with T2*-corrected Dixon (3-point Dixon) and 6-Echo Interference Dixon (6-point Dixon) pulse sequences, including HISTO, were applied in sequence. Using fat percentages obtained from each pulse sequence, levels of fatty liver were classified as: non-fatty liver, < 5 %; mild fatty liver, > 5 but < 31 %; and severe fatty liver, > 31 %. The correlation between methods was calculated with a correlation coefficient (R (2)): HISTO and 3-point Dixon, 0.936 (p < 0.001); HISTO and 6-point Dixon, 0.944 (p < 0.001); and 3-point Dixon and 6-point Dixon, 0.984 (p < 0.001). The HISTO, which was used to investigate fat percentages after T2* correction, showed a high correlation with 3-point Dixon and 6-point Dixon, suggesting that the multi-echo method is useful for accurately determining fat percentages.
机译：这项研究比较了HISTO方法和化学位移成像方法，3回波3D梯度回波序列与T2 *校正的Dixon（3点Dixon）和6回波干扰Dixon磁共振（MR）成像（ 6点Dixon）方法，通过多回波T2 *校正的单体素光谱组织学（HISTO）评估脂肪肝定量的临床意义。共有21位肝捐赠者接受了MR成像检查。所有研究均使用3-T MR系统（Siemens Healthcare Tim Verio，德国埃尔兰根）。为了评估脂肪百分比，依次应用了具有T2 *校正的Dixon（3点Dixon）和6-Echo Interference Dixon（6点Dixon）脉冲序列（包括HISTO）的3回波3D梯度回波序列。使用从每个脉冲序列获得的脂肪百分比，将脂肪肝的水平归类为：非脂肪肝，<5％;轻度脂肪肝，> 5但<31％;重度脂肪肝，> 31％。方法之间的相关性通过相关系数（R（2））计算：HISTO和3点Dixon，0.936（p <0.001）; HISTO和6点Dixon，0.944（p <0.001）; 3点Dixon和6点Dixon，0.984（p <0.001）。用于校正T2 *后的脂肪百分比的HISTO与3点Dixon和6点Dixon具有高度相关性，这表明多回波法可用于准确确定脂肪百分比。

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