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The impact of epilepsy on the quality of life of patients with meningioma: A systematic review

机译:癫痫对脑膜瘤患者生活质量的影响:系统评价

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Quality of life (QoL) is regarded as an important outcome measure in meningioma, and studies have investigated the role of various clinical and demographic factors. Epilepsy is known to impair quality of life but the impact of epilepsy on quality of life in a meningioma population is not well defined. The aim of this systematic review is to identify and summarise the current literature on meningioma, epilepsy and quality of life. A PubMed search was performed that identified 162 articles. Only 4 articles relevant to meningioma, epilepsy and QoL were found and each were analysed in terms of design, data, findings and conclusions. Each article was different in terms of study population, aims and outcome measure, but all suggest that epilepsy has an impact on quality of life. Anti-epileptic drugs, uncontrolled seizures and cognitive dysfunction may be particularly significant. The identified articles were weakened by small sample size, short follow-up, a lack of recorded epilepsy variables and the use of quality of life measures that are either too specific or not validated. Future studies are warranted to improve understanding in this topic, aid clinical decisions and improve QoL in these patients.
机译:生活质量(QoL)被认为是脑膜瘤的重要结局指标,并且研究已经调查了各种临床和人口统计学因素的作用。已知癫痫会损害生活质量,但癫痫对脑膜瘤人群生活质量的影响尚不明确。本系统综述的目的是鉴定和总结有关脑膜瘤,癫痫和生活质量的最新文献。进行PubMed搜索,发现162条文章。仅发现了4篇与脑膜瘤,癫痫和QoL相关的文章,并对每篇文章的设计,数据,发现和结论进行了分析。每篇文章的研究人群,目的和结果衡量指标均不同,但均表明癫痫症会影响生活质量。抗癫痫药,无法控制的癫痫发作和认知功能障碍可能特别重要。由于样本量小,随访时间短,缺乏记录的癫痫变量以及使用过于具体或未经验证的生活质量测量方法,所识别的物品均被削弱。有必要进行进一步的研究,以增进对此主题的理解,帮助临床决策并改善这些患者的生活质量。

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