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首页> 外文期刊>International Poultry Production >Synergisms of phytogenic feed additives and antibiotic growth promoters
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Synergisms of phytogenic feed additives and antibiotic growth promoters

机译：植物饲料添加剂和抗生素生长促进剂的协同作用

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Intensive livestock production has brought about many challenges for both man and animals. Along with discussions on housing conditions and stocking densities, man has become more conscious of exploring the maximum genetic potential of agricultural livestock irrespective of the physiological and other stresses they are confronted with.Animals need to withstand these odds and maintain high productivity. This challenge certainly demands specific and novel agents that can help animals withstand difficult times and maintain high levels of productivity.For decades, sub-therapeutic doses of antibiotics have been used to reduce challenges (diseases) for increasing or maintaining performance. The key target of using antibiotic growth promoters (AGPs) is to increase nutrient digestibility by suppressing bacterial growth in the gut (by interfering with the synthesis of DNA, RNA and proteins).Besides antibacterial effects, AGPs play a central role in suppressing inflammation that is signalled by the release of catabolic hormones and leads to significant reduction in muscle mass.
机译：集约化畜牧业给人类和动物带来了许多挑战。在讨论住房条件和放养密度的同时，人们变得越来越意识到探索牲畜的最大遗传潜力，而不论他们面临的生理和其他压力如何。动物需要承受这些困难并保持高生产率。当然，这一挑战需要特定且新颖的药物来帮助动物抵御困难时期并保持高水平的生产力。数十年来，亚治疗剂量的抗生素已被用于减少提高或维持性能的挑战（疾病）。使用抗生素生长促进剂（AGP）的主要目标是通过抑制肠道细菌的生长（通过干扰DNA，RNA和蛋白质的合成）来提高营养物质的消化率。除抗菌作用外，AGP在抑制炎症中起着核心作用。分解代谢激素的释放会发出信号，导致肌肉质量显着降低。

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