• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International Journal of Zoology >Spermatogenic Waves and Expression of AR ERs in Germ Cells of Podarcis sicula
【24h】

Spermatogenic Waves and Expression of AR ERs in Germ Cells of Podarcis sicula

机译：刺槐生殖细胞中生精波和AR ERs的表达

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Androgens are considered the main hormones that regulate spermatogenesis, but a lot of evidence confers to estrogen a key role in this process. In the testis of the seasonal breeder lizard Podarcis sicula we analyzed by means of in situ hybridizationthe expression of the androgen receptor (AR) and of the two types, a and 6, of the estrogen receptors (ERs) throughout the three periods of the annual cycle: mating (spring-early summer), postmating-refractory (late summer), and autumnal recrudescence. The results show that during the mating period AR and ERs are expressed in all germ cells present in the tubules from spermatogonia to spermatozoa. During the postmating-refractory period, when only spermatogonia are present in the tubules, almost all express ERs and very few AR mRNA. During the autumnal recrudescence the localization of AR and ERs is the same of the mating period except for the population of the primary spermatocytes. The expression of the investigated receptors is peculiar in these cells that are positive in the middle-late pachytene stage of the meiotic prophase and negative in preleptotene. A possible functional role of the observed differences during spermatogenesis and in the spermatozoa is also discussed.
机译：雄激素被认为是调节精子发生的主要激素，但许多证据表明雌激素在此过程中起关键作用。在季节性繁殖者蜥蜴Podarcis sicula的睾丸中，我们通过原位杂交分析了全年三个时期中雄激素受体（AR）以及雌激素受体（ER）的两种类型以及雌激素受体（ER）的表达。周期：交配（春季至夏季初），交配期至难治性（夏季初夏）和秋季复发。结果表明，在交配期间，从精原细胞到精子，小管中存在的所有生殖细胞中都表达了AR和ER。在交配后不应期，当肾小管中仅存在精原细胞时，几乎全部表达ER，而AR mRNA则很少。在秋季再发期间，除了原代精母细胞的种群外，AR和ER的定位与交配期相同。在这些细胞中，所研究的受体的表达是特有的，在减数分裂前期的中晚期粗线期为阳性，而在前瘦素中为阴性。还讨论了在精子发生期间和精子中观察到的差异的可能功能作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号