...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of obstetric anesthesia >Effect of varying doses of fentanyl with low dose spinal bupivacaine for caesarean delivery in patients with pregnancy-induced hypertension.
【24h】

Effect of varying doses of fentanyl with low dose spinal bupivacaine for caesarean delivery in patients with pregnancy-induced hypertension.

机译：不同剂量的芬太尼低剂量布比卡因脊髓对妊娠高血压综合征患者的剖腹产效果。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The purpose of this study was to evaluate haemodynamic stability, perioperative analgesia and neonatal outcome following intrathecal 0.5% bupivacaine 7.5 mg with varying doses of fentanyl, in parturients with pregnancy-induced hypertension. Forty-five parturients with pregnancy-induced hypertension scheduled for caesarean section were randomly allocated to receive 7.5 mg bupivacaine with saline 1 mL (group B), fentanyl 10 microg (group Bf10) or fentanyl 20 microg (group Bf20) intrathecally. Heart rate, blood pressure, and sensory block were recorded at regular intervals. Pain, nausea, vomiting, pruritus or any other side effects were sought. Neonatal outcome was assessed using Apgar score and umbilical artery blood gas analysis. Adequate surgical anaesthesia was established in all three groups. There was a statistically significant fall in mean arterial pressure in all three groups within 4-6 min of subarachnoid block (P<0.05), but the decrease in MAP was <20% of baseline in all three groups. Pain and discomfort during surgery were experienced more frequently in group B than in groups Bf10 and Bf20 (P<0.05). Duration of postoperative analgesia was significantly longer in group Bf20 (5.55+/-1.18 h) than in group Bf10 (3.97+/-2.12 h) and group B (3.27+/-1.8 h) (P<0.05). Neonatal outcome was similar in the three groups. Intrathecal fentanyl with low dose bupivacaine provides good surgical anaesthesia and prolongs the duration of analgesia without haemodynamic or neonatal compromise in patients with pregnancy-induced hypertension undergoing caesarean delivery.
机译：这项研究的目的是评估在鞘内注射0.5％布比卡因7.5 mg，不同剂量的芬太尼的鞘内注射后，在妊娠高血压综合征中的血流动力学稳定性，围手术期镇痛和新生儿结局。计划剖腹产的四十五名有妊娠高血压综合征的产妇在鞘内随机分配接受7.5 mg布比卡因和生理盐水1 mL（B组），芬太尼10 microg（Bf10组）或芬太尼20 microg（Bf20组）。定期记录心率，血压和感觉障碍。寻求疼痛，恶心，呕吐，瘙痒或任何其他副作用。使用Apgar评分和脐动脉血气分析评估新生儿结局。在所有三组中均建立了足够的手术麻醉。在蛛网膜下腔阻滞的4-6分钟内，所有三组的平均动脉压都有统计学意义的下降（P <0.05），但所有三组的MAP下降均<基线的20％。与Bf10和Bf20组相比，B组的手术过程中疼痛和不适的发生频率更高（P <0.05）。 Bf20组（5.55 +/- 1.18 h）的术后镇痛持续时间明显长于Bf10组（3.97 +/- 2.12 h）和B组（3.27 +/- 1.8 h）（P <0.05）。三组的新生儿结局相似。鞘内注射芬太尼低剂量布比卡因可为剖宫产分娩的妊娠高血压综合征患者提供良好的手术麻醉，并延长镇痛持续时间，而无血流动力学或新生儿损害。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号