Elestat (epinastine HCl ophthalmic solution 0.05%) as a therapeutic for allergic conjunctivitis.

Trattler WB; Luchs J; Majmudar P

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Elestat (epinastine HCl ophthalmic solution 0.05%) as a therapeutic for allergic conjunctivitis.

机译：Elestat（盐酸依帕斯汀眼用溶液0.05％）作为过敏性结膜炎的治疗剂。

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Epinastine 0.05% ophthalmic solution (Elestat, Inspire Pharmaceuticals Inc, Durham, NC) is the most recently approved topical therapy for ocular allergies, having been available in the US market since February 2004. It is indicated for the prevention of itching associated with allergic conjunctivitis and is approved for twice-daily dosing. This article reviews the impact of allergic conjunctivitis and its pathophysio-logy, the mechanism of action of epinastine, and clinical attributes of topical ophthalmic epinastine including its efficacy, safety, and impact on the

机译：Epinastine 0.05％眼药水（Elestat，Inspire Pharmaceuticals Inc，达勒姆，北卡罗来纳州）是最近批准的眼部过敏局部治疗方法，自2004年2月起在美国上市。该药可预防与过敏性结膜炎相关的瘙痒。并被批准每天两次给药。本文综述了变应性结膜炎的影响及其病理生理学，表位碱的作用机制以及局部眼用表位晶状体的临床特征，包括其有效性，安全性以及对结膜炎的影响。

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《International ophthalmology clinics》 |2006年第4期|共13页
作者
Trattler WB; Luchs J; Majmudar P;
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正文语种 eng
中图分类眼科学;
关键词
Animals; Conjunctivitis; Allergic; Dibenzazepines; Dose-Response Relationship; Drug; 动物; 结膜炎; 变应性; 二苯氮ZHUO类; 剂量效应关系; 药物; 组胺H1拮抗剂; 咪唑类;

机译：Animals;Conjunctivitis;Allergic;Dibenzazepines;Dose-Response Relationship;Drug;动物;结膜炎;变应性;二苯氮|ZHUO|类;剂量效应关系;药物;组胺H1拮抗剂;咪唑类;

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1. Elestat (epinastine HCl ophthalmic solution 0.05%) as a therapeutic for allergic conjunctivitis. [J] . Trattler WB, Luchs J, Majmudar P International ophthalmology clinics . 2006,第4期

机译：Elestat（盐酸依帕斯汀眼用溶液0.05％）作为过敏性结膜炎的治疗剂。
2. Efficacy of olopatadine HCI 0.1%, ketotifen fumarate 0.025%, epinastine HCI 0.05%, emedastine 0.05% and fluorometholone acetate 0.1% ophthalmic solutions for seasonal allergic conjunctivitis: a placebo-controlled environmental trial [J] . Mehmet Borazan, Aylin Karalezli, Yonca Aydin Akova, Acta ophthalmologica Scandinavica . 2009,第5期

机译：盐酸奥洛他定盐酸盐0.1％，富马酸酮替芬0.025％，盐酸依帕替丁盐酸盐0.05％，依莫司汀0.05％和乙酸氟甲羟戊酮0.1％眼药水对季节性过敏性结膜炎的作用：安慰剂对照环境试验
3. Efficacy and tolerability of ophthalmic epinastine: a randomized, double-masked, parallel-group, active- and vehicle-controlled environmental trial in patients with seasonal allergic conjunctivitis. [J] . Whitcup SM, Bradford R, Lue J, Clinical therapeutics . 2004,第1期

机译：眼药性癫痫的功效和耐受性：季节性变应性结膜炎患者的一项随机，双掩蔽，平行组，主动和媒介对照的环境试验。
4. Influence of the HClO_4 Concentration Over the Morphology and Growth of TiO_2 Anodic Porous Films Formed in 5 mMHF/xMHClO_4 (0.05M ≤ x ≤ 1M) [C] . Prospero Acevedo-Pena, I. Gonzalez MES 26: Electrochemistry as a tool for sustainable development . 2011

机译：HClO_4浓度对5 mMHF / xMHClO_4（0.05M≤x≤1M）中形成的TiO_2阳极多孔膜的形貌和生长的影响
5. The therapeutic effects of a suppressor of cytokine signaling 1 mimetic peptide in experimental allergic encephalomyelitis, a murine model of multiple sclerosis. [D] . Jager, Lindsey Delores. 2010

机译：细胞因子信号传导1模拟肽抑制剂在实验性变应性脑脊髓炎（一种多发性硬化的小鼠模型）中的治疗作用。
6. Double-masked randomized parallel-group study comparing olopatadine 0.1 ophthalmic solution with cromolyn sodium 2 and levocabastine 0.05 ophthalmic preparations in children with seasonal allergic conjunctivitis [O] . Giorgio Ciprandi, Darell Turner, Robert D. Gross 2004

机译：对季节性过敏性结膜炎患儿进行的双盲平行平行分组研究比较了奥洛他定0.1％眼药水与2％的克罗莫林钠和0.05％的左卡泊汀的眼用制剂
7. Role of topical ophthalmic solutions (0.1) olopatadine hydrochloride and (0.05) epinastine hydrochlloride in vernal keratoconjuntivitis [O] . Yusuf Rizvi, Tahir Husain Ansari 2020

机译：常规眼科溶液（0.1％）盐酸盐盐酸盐和（0.05％）盐酸在春宫角膜炎肝炎中的作用

Elestat (epinastine HCl ophthalmic solution 0.05%) as a therapeutic for allergic conjunctivitis.

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