首页> 外文期刊>International Union of Crystallography newsletter >Early Days of Protein Crystallography in Canada
【24h】

Early Days of Protein Crystallography in Canada

机译:加拿大蛋白质晶体学的早期

获取原文
获取原文并翻译 | 示例
       

摘要

Protein crystallography in Canada dates back to the 1960's. At the Physics Division of NRC in Ottawa there was already a strong contingent of small-molecule crystallographers led by W.F. Barnes. A member of that group, Maria Przybylska, moved to the Chem-istry Division and embarked on a major protein crystallography project, a complex between hemoglobin and haptoglobin. George Birnbaum, who joined her group in 1966, became involved in this project by isolating and identifying the monomer haptoglobin 1-1 obtained from ascites fluids of cancer patients. Many years were devoted to obtaining suitable crystals of the Hb:Hp complex but without success, and the structure was never solved.
机译:加拿大的蛋白质晶体学可以追溯到1960年代。在渥太华的NRC物理部门,已经有一支由W.F.领导的强大的小分子晶体学家队伍。巴恩斯。该小组的成员Maria Przybylska移居化学部,着手进行一项主要的蛋白质晶体学计划,即血红蛋白和触珠蛋白之间的复合物。乔治·比恩鲍姆(George Birnbaum)于1966年加入她的小组,通过分离和鉴定从癌症患者腹水中获得的单体触珠蛋白1-1参与了该项目。多年来致力于获得合适的Hb:Hp配合物晶体,但没有成功,并且该结构从未解决。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号