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首页> 外文期刊>Investigative ophthalmology & visual science >Myopia and incident cataract and cataract surgery: the blue mountains eye study.
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Myopia and incident cataract and cataract surgery: the blue mountains eye study.

机译：近视和白内障事件及白内障手术：蓝山眼研究。

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PURPOSE. To assess whether an association exists between myopia and incident cataract and cataract surgery in an older population-based cohort study. METHODS. The Blue Mountains Eye Study examined 3654 participants aged 49 years or more during 1992 to 1994 and then 2334 (75.1%) of the survivors after 5 years. A history of using eyeglasses for clear distance vision was obtained. Objective refraction was performed with an autorefractor, followed by subjective refraction with a logarithm of minimum angle of resolution (logMAR) chart. Emmetropia was defined as a spherical equivalent refraction between +1 D and -1 D, hyperopia as more than +1 D, and myopia as less than -1 D. Slit lamp and retroillumination lens photographs were graded for presence of cortical, nuclear, or posterior subcapsular cataract, according to the Wisconsin Cataract Grading System. Generalized estimating equation models analyzed data by eye. RESULTS. There was a statistically significant association between high myopia (-6 D or less) and incident nuclear cataract (odds ratio [OR] 3.3, 95% confidence interval [CI] 1.5-7.4). Incident posterior subcapsular cataract was associated with any myopia (OR 2.1, 95% CI 1.0-4.8), moderate to high myopia (-3.5 D or less, OR 4.4, 95% CI 1.7-11.5), and use of distance glasses before age 20 (OR 3.0, 95% CI 1.0-9.3), after adjustment for multiple potential confounders, including severity of nuclear opacity. Incident cataract surgery was significantly associated with any myopia (OR 2.1, 95% CI 1.1-4.2) as well as moderate (-3.5 to more than -6D; OR 2.9, 1.2-7.3) and high myopia (OR 3.4, 95% CI 1.0-11.3). CONCLUSIONS. These epidemiologic data provide some evidence of an association between myopia and incident cataract and cataract surgery, after adjustment for multiple confounders and severity of nuclear opacity. These data support other cross-sectional and longitudinal population-based findings.
机译：目的。在一项较早的基于人群的队列研究中，要评估近视与白内障和白内障手术之间是否存在关联。方法。蓝山眼研究调查了1992年至1994年间3654名年龄在49岁或以上的参与者，然后调查了5年后2334名（75.1％）幸存者。获得了使用眼镜进行近距离远视的历史。使用自动折射仪进行客观折射，然后使用对数最小分辨率角（logMAR）图的主观折射。正视是指在+1 D和-1 D之间的球面等效屈光度，远视是大于+1 D，近视是小于-1D。裂隙灯和反光镜照片按皮质，核或反光的存在进行分级。根据威斯康星州白内障分级系统，后囊后白内障。广义估计方程模型通过肉眼分析数据。结果。高度近视（-6 D或更小）与入射核性白内障之间存在统计学上的显着关联（赔率[OR] 3.3，95％置信区间[CI] 1.5-7.4）。后囊内白内障的发生与任何近视（OR 2.1，95％CI 1.0-4.8），中至高度近视（-3.5 D或以下，OR 4.4，95％CI 1.7-11.5）有关，并且在年龄之前使用远距离眼镜在针对多个潜在的混杂因素（包括核不透明性的严重程度）进行调整后，得出20（OR 3.0，95％CI 1.0-9.3）。白内障手术与任何近视（OR 2.1，95％CI 1.1-4.2）以及中度（-3.5至-6D以上; OR 2.9，1.2-7.3）和高度近视（OR 3.4，95％CI）显着相关1.0-11.3）。结论。这些流行病学数据提供了一些证据，这些证据表明在调整了多个混杂因素和核不透明性的严重性之后，近视与白内障和白内障手术相关。这些数据支持其他基于人口的横断面和纵向调查结果。

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