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Plasticity and the functional reorganization of the human brain.

机译:人脑的可塑性和功能重组。

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摘要

Stroke is a leading cause of long-term disability in adults worldwide. The mechanisms of impairment and recovery are not well understood, but there is growing interest in the role that central nervous system reorganization might play. Functional magnetic resonance imaging and transcranial magnetic stimulation allow the non-invasive study of the working human brain, and studies in humans suggest that functionally relevant adaptive changes occur in cerebral networks following stroke. An understanding of how these changes influence the recovery process will facilitate the development of novel therapeutic techniques that are based on neurobiological principles and which are designed to minimise impairment in appropriately targeted patients suffering from stroke.
机译:中风是全球成年人长期残疾的主要原因。损伤和恢复的机制尚不十分清楚,但人们越来越关注中枢神经系统重组可能发挥的作用。功能磁共振成像和经颅磁刺激可以对正在工作的人脑进行非侵入性研究,而对人体的研究表明中风后脑网络中发生了功能相关的适应性变化。对这些变化如何影响恢复过程的理解将促进基于神经生物学原理的新型治疗技术的发展,该技术旨在使患有中风的适当靶向患者的损害最小化。

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