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首页> 外文期刊>International journal of surgical pathology >Hyaline Globules in Mammary Myofibroblastoma: A Case Report
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Hyaline Globules in Mammary Myofibroblastoma: A Case Report

机译:乳腺肌成纤维细胞瘤中的透明质酸球:一例报告

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摘要

A 52-year-old otherwise healthy woman presented with a solitary firm mass in the right breast. Histopathological evaluation of the 1.5-cm mass showed a mammary myofibroblastoma of the conventional spindle-cell type. High-power examination of hematoxylin-eosin-stained sections showed round, eosinophilic, intracytoplasmic, as well as extracellular, hyaline globules. These 5- to 20-mu m globules appeared gray with a pinkish rim on Masson's trichrome stain. Immunohistochemically, the hyaline globules were strongly reactive with smooth muscle myosin heavy chain, desmin, and caldesmon. Histologically similar inclusion bodies have been reported in phylloides tumors-including those with myoid differentiation. To our knowledge, this is the first description of hyaline globules, a peculiar histological curiosity with no known clinical significance, in mammary myofibroblastoma.
机译:一名52岁健康的女性,右乳房出现孤立性硬块。 1.5cm肿块的组织病理学评价显示常规梭形细胞型乳腺肌成纤维细胞瘤。苏木精-伊红染色切片的高倍检查显示,圆形,嗜酸性,胞浆内以及胞外透明球状。这些5至20微米的小球呈灰色,在Masson的三色染色剂上呈粉红色边缘。免疫组织化学分析,透明小球与平滑肌肌球蛋白重链,结蛋白和卡尔德斯蒙反应强烈。组织学上相似的包涵体已被报道在类小瘤肿瘤中,包括那些具有类肌体分化的肿瘤。据我们所知,这是对乳腺肌成纤维细胞瘤中透明球的首次描述,透明球是一种特殊的组织学好奇心,没有已知的临床意义。

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