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首页> 外文期刊>International journal of surgical pathology >Multilocular cystic nephroma and multicystic clear cell carcinoma: two faces of the Roman god Janus?
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Multilocular cystic nephroma and multicystic clear cell carcinoma: two faces of the Roman god Janus?

机译:多房囊性肾癌和多囊性透明细胞癌:罗马神贾纳斯的两张面孔?

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A 37-year-old man presented with a mild persistent left flank pain and a painful left multilocular cystic renal mass was referred to our hospital. After a series of examinations, including abdominal ultrasound, intravenous pyelography, as well as computed tomography, and despite the benign appearance of the lesion on radiological evaluation, he underwent surgical exploration. A partial nephrectomy has been finally performed. On microscopy, the lesion was found to be a multilocular cystic nephroma (MLCN) consisting of multiple cysts with a maximum diameter from 0.3 to 2 cm. The cystic walls were composed of fibrous and partly collagenous tissue with a few, scattered inflammatory cells (Figure. 1). The flat and cuboidal cells of lining epithelium were generally normal, showing no atypia or mitosis. Focally, however, the lining cells exhibited the typical features of those of clear cell carcinoma of the kidney. Few microscopic aggregates of cells with similar appearance were found in the stroma (Figure. 2). The surgical margins were free of tumor.
机译:一名37岁的男性出现轻度持续性左胁腹疼痛,左侧多囊性胆囊性肾脏肿痛,被转诊至我院。在进行了一系列检查(包括腹部超声检查,静脉肾盂造影和计算机断层扫描)后,尽管在影像学评估中病变的外观是良性的,他还是进行了手术探查。终于完成了部分肾切除术。在显微镜下,病变为多眼囊性肾瘤(MLCN),由最大直径为0.3至2 cm的多个囊肿组成。胆囊壁由纤维性和部分胶原性组织以及少量散在的炎症细胞组成(图1)。衬里上皮的扁平和长方体细胞通常是正常的,没有显示出非典型性或有丝分裂。然而,从表面上看,内衬细胞表现出肾透明细胞癌的典型特征。在基质中几乎没有发现具有相似外观的细微细胞聚集体(图2)。手术切缘无肿瘤。

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