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首页> 外文期刊>International journal of surgical pathology >Images in pathology. Mixed tumour of the skin with extensive ossification and bone marrow formation on the scalp of a young patient.
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Images in pathology. Mixed tumour of the skin with extensive ossification and bone marrow formation on the scalp of a young patient.

机译：病理图像。一名年轻患者头皮上广泛的骨化和骨髓形成的混合性皮肤肿瘤。

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Mixed tumor of the skin (MTS) is an uncommon adnexal tumor with both epithelial and mesenchymal component, presenting in the head and neck region of middle-aged and elderly patients, usually arising in the nose, cheek, and upper lip. A 28-year-old white man presented with a painless, slow growing nodule, 1 cm in diameter, on his scalp, with some areas of calcification. Histology showed a lobulated tumor composed of branching tubular structures lined by 2 layers of epithelial cells, cuboidal in the luminal layer and flattened at the periphery, within a chondromyxoid stroma (Figure 1A). No cytologic atypia, necrosis, or mitotic figures were found. In the setting of this lesion an area of bone formation (Figures 1B and 1C) with hypocellular fat marrow (Figure 1D) was observed. The bone occupied more than one quarter of the entire lesion and was formed without intervening cartilage. All these features were consistent with the diagnosis of benign MTS with ossification and bone marrow formation.
机译：皮肤混合瘤（MTS）是一种罕见的附件肿瘤，同时具有上皮和间充质成分，出现在中老年患者的头颈部区域，通常发生在鼻子，脸颊和上唇。一名28岁的白人在头皮上出现无痛，缓慢生长的结节，直径1厘米，有钙化区域。组织学显示，在软骨粘膜基质内，小叶状肿瘤由分支状管状结构组成，该结构由两层上皮细胞排列，在腔层呈立方体状，在边缘呈扁平状（图1A）。没有发现细胞学上的异型性，坏死或有丝分裂图。在该病灶的设置中，观察到了骨形成区域（图1B和1C）和低细胞脂肪的骨髓（图1D）。骨头占据了整个病变的四分之一以上，并且形成时没有介入软骨。所有这些特征均与诊断为骨化和骨髓形成的良性MTS一致。

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