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首页> 外文期刊>Iranian journal of public health. >Enterovirases in Acute Myocardlal Infarction
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Enterovirases in Acute Myocardlal Infarction

机译:急性心肌梗死中的肠病毒

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Background: Human enteroviruses (EVs) may have a role as a possible risk factor in the pathogenesis of MI. The aim of this study was to evaluate the presence of enterovims genomic RNA in peripheral blood samples of patients with acute myocardial infarction (MI).Methods: We investigated the presence of enterovirus genomic RNA in the peripheral blood of 115 patients with acute MI hospitalized in the Coronary Care Unit of Imam Reza and Ghaem University Hospitals (Mashhad, Iran) by RT-PCR using the virus specific primers.Results: The subjects' mean (±SD) age was 63.5 (±9.4) years (range: 38-82) and 38.3 % of the subjects were female. Of 115 patient specimens, 3 (2.6%) were positive in RT-PCR. Conclusion: The prevalence of enterovirus in MI patients is considerable. More investigations are needed to determine the causal role of enteroviruses in MI.
机译:背景:人类肠道病毒(EV)可能是MI发病机制中的潜在危险因素。这项研究的目的是评估急性心肌梗塞(MI)患者外周血中肠病毒基因组RNA的存在。方法:我们调查了115例急性心肌梗死住院患者的外周血中肠病毒基因组RNA的存在。使用病毒特异性引物通过RT-PCR方法在伊玛目礼扎和Ghaem大学医院的冠心病监护室进行了RT-PCR结果:受试者的平均(±SD)年龄为63.5(±9.4)岁(范围:38-82) ),其中38.3%为女性。在115个患者样本中,有3个(2.6%)在RT-PCR中呈阳性。结论:心肌梗死患者中肠病毒的流行是相当大的。为了确定肠病毒在心肌梗死中的作用,还需要进行更多的研究。

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