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首页> 外文期刊>Iranian journal of public health. >Effect of Pregnancy on the Levels of Blood Cadmium and Lead: analysis of 2006-2011 Nanjing Maternity and Child Health Care Hospital Survey Data
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Effect of Pregnancy on the Levels of Blood Cadmium and Lead: analysis of 2006-2011 Nanjing Maternity and Child Health Care Hospital Survey Data

机译：妊娠对血镉和铅水平的影响：2006-2011年南京妇幼保健院调查数据分析

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Abstract Background: Prenatal lead exposure could not only affect various organ systems of the mother, but also provide a plumbeous environment for the fetus and newborns, and may affect the fetus in a number of detrimental ways. The aim of this study was to adequately determine the interaction between these factors arid risky behaviors such as smoking. Methods: Data from Nanjing Maternity and Child Health Care Hospital survey during the years of 2006-2011 were used (n = 4400) to evaluate the effections of age, parity, body mass index (BMT), race/ethnicity, pregnancy, iron (Fe) storage status and smoking status on the consumption of the levels of blood cadmium (Cd) and lead (Pb) of females aged 16-35yr old. The blood samples were sent to determine blood lead / cadmium concentration by the Inductively Coupled Plasma Mass Spectrometry (ICP-MS) . STATA 12.1 software (www. stata.com) was used to fit regression models for each of the two metals. Results: For both of the two metals, age was positively while BMI was negatively associated with the levels of these metals in blood. Smokers showed statistically significantly higher levels of Cd and Pb ( P=0.007) , while irrespective of race/ethnicity and Fe storage status as compared to nonsmokers. Conclusion: Novel to this study, pregnancy was found to be associated with significantly lower levels of Cd and Pb, while irrespective of race/ethnicity and Fe storage status as compared to non-pregnant females. It is conceivable that pregnancy could thus accelerate clearance of these metals in the blood.
机译：摘要背景：产前铅暴露不仅会影响母亲的各个器官系统，而且会为胎儿和新生儿提供铅酸的环境，并可能以多种有害方式影响胎儿。本研究的目的是充分确定这些因素与危险行为（如吸烟）之间的相互作用。方法：采用南京市妇幼保健院2006-2011年的调查数据（n = 4400）评估年龄，胎次，体重指数（BMT），种族/民族，怀孕，铁的影响。 （Fe）储存状态和吸烟状态对16-35岁女性的血镉（Cd）和铅（Pb）消耗水平的影响。通过感应耦合等离子体质谱法（ICP-MS）发送血样以确定血铅/镉浓度。使用STATA 12.1软件（www.stata.com）拟合两种金属每种的回归模型。结果：对于这两种金属，年龄都是正的，而BMI与血液中这些金属的含量呈负相关。与不吸烟者相比，吸烟者的Cd和Pb含量在统计学上显着更高（P = 0.007），而与种族/民族和Fe储存状态无关。结论：这项研究的新颖之处在于，与非怀孕女性相比，与种族/民族和铁的储存状态无关，怀孕与Cd和Pb水平显着降低有关。可以想象怀孕因此可以加速血液中这些金属的清除。

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