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首页> 外文期刊>Iranian journal of public health. >Gender Differences in the Risk of Coronary Artery Disease in Iran
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Gender Differences in the Risk of Coronary Artery Disease in Iran

机译：伊朗冠状动脉疾病风险的性别差异

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Background: Given gender differences in the risk of coronary artery disease (CAD), the present study sought to investigate these dissimilarities amongst patients who underwent angiography at a major, tertiary heart hospital in Iran. Methods: Between 2005 and 2010, 44,820 patients who underwent coronary angiography were enrolled in a registry. Pre-procedural data such as demographics, CAD risk factors, presenting symptoms, and laboratory tests, as well as post-procedural data were collected. The data were, subsequently, compared between the men and women. Results: Out of the 44,820 patients (16,378 women), who underwent coronary angiography, 37,358 patients (11,995 women) had CAD. Amongst the CAD patients, the females were not only significantly older, less educated, and more overweight than were the males but also had higher levels of triglyceride, cholesterol, low-density lipoprotein, high-density lipoprotein, and fasting blood sugar (P< 0.001). Of all the risk factors, hypertension and diabetes mellitus showed the strongest association in our female CAD patients (OR=3.45, 95%CI: 3.28-3.61 and OR=2.37, 95%CI: 2.26-2.48, respectively). Acute coronary syndrome was more prevalent in the men (76.1% vs. 68.6%, P< 0.001), and chronic stable angina was more frequent in the females (31.4% vs. 23.9%, P< 0.001). With respect to post-procedural recommendations, the frequency of recommendations for non-invasive modalities was higher in the females (20.1% vs. 18.6%, P< 0.001).Conclusion: Hypertension and diabetes mellitus had the strongest association with CAD in our female patients. In the extensive CAD patients, medical treatment was recommended to the women more often.
机译：背景：鉴于在冠心病（CAD）风险方面的性别差异，本研究旨在调查在伊朗一家大型三级心脏医院接受血管造影术的患者之间的这些差异。方法：2005年至2010年间，对44,820例行冠状动脉造影的患者进行了登记。收集了诸如人口统计学，CAD危险因素，症状表现和实验室检查等术前数据，以及术后数据。随后，对男女之间的数据进行了比较。结果：在接受冠状动脉造影的44,820例患者（16,378名女性）中，有37,358例患者（11,995名女性）患有CAD。在冠心病患者中，女性不仅比男性年龄大，受教育程度低，而且超重更多，而且甘油三酸酯，胆固醇，低密度脂蛋白，高密度脂蛋白和空腹血糖水平也较高（P < 0.001）。在所有危险因素中，高血压和糖尿病在我们的女性CAD患者中显示出最强的关联性（分别为OR = 3.45，95％CI：3.28-3.61和OR = 2.37，95％CI：2.26-2.48）。急性冠状动脉综合征在男性中更为普遍（76.1％vs. 68.6％，P <0.001），而慢性稳定型心绞痛在女性中更为常见（31.4％vs. 23.9％，P <0.001）。在手术后推荐方面，女性无创治疗的推荐频率更高（20.1％比18.6％，P <0.001）。结论：高血压和糖尿病与女性CAD的关联最强耐心。在广泛的CAD患者中，更经常建议女性接受药物治疗。

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