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首页> 外文期刊>Echocardiography. >Dobutamine stress echocardiography Doppler estimation of cardiac diastolic function: a simultaneous catheterization correlation study.
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Dobutamine stress echocardiography Doppler estimation of cardiac diastolic function: a simultaneous catheterization correlation study.

机译：多巴酚丁胺负荷超声心动图多普勒估计的心脏舒张功能：同步导管相关性研究。

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BACKGROUND: Doppler echocardiography using the ratio of early diastolic transmitral velocity to early diastolic mitral annular tissue velocity (E/E') is routinely used to evaluate left ventricular (LV) filling pressures at rest. We tested the hypothesis that measurement of E/E' in patients undergoing dobutamine stress echocardiography (DSE) will detect changes in LV filling pressures. METHODS: In this prospective study, 16 patients with normal LV ejection fraction and normal coronary arteries by angiography underwent a standard DSE protocol with simultaneous LV filling pressure monitoring with a fluid filled pigtail catheter. Doppler echocardiographic assessment of LV diastolic function was performed using E/E' at rest and during DSE. RESULTS: The average age of the study participants was 57 +/- 8 years. Average heart rate was 61 +/- 11 bpm at baseline and 141 +/- 12 bpm at peak stress. LV mean diastolic pressure decreased from 12.3 +/- 2.6 mmHg at baseline to 9.0 +/- 2.3 mmHg at peak stress (P = 0.0001). Baseline E/E' at the septum and lateral annulus were 8.7 +/- 2.2 and 7.5 +/- 1.9 and during peak stress were 8.3 +/- 3.1 and 7.9 +/- 3.5, respectively. There was no significant change in E/E' at either the septum or the lateral annulus (P = 0.55, P = 0.66). There was no significant correlation between LV mean diastolic pressure and E/E' with dobutamine stress. CONCLUSIONS: In patients with normal LV ejection fraction and no significant coronary artery disease undergoing DSE, the ratio of early diastolic transmitral velocity to early diastolic tissue velocity (E/E') at peak stress with dobutamine does not predict changes in LV filling pressures.
机译：背景：多普勒超声心动图使用舒张早期传输速度与舒张早期二尖瓣环状组织速度（E / E'）之比来常规评估静止时左心室（LV）充盈压。我们检验了以下假设，即接受多巴酚丁胺应力超声心动图（DSE）的患者的E / E'测量将检测到左室充盈压的变化。方法：在这项前瞻性研究中，通过血管造影术对16例左室射血分数正常且冠状动脉正常的患者进行了标准DSE方案，并用充液的尾纤导管同时监测了左室充盈压。在休息时和DSE期间使用E / E'对左室舒张功能进行多普勒超声心动图评估。结果：研究参与者的平均年龄为57 +/- 8岁。平均心率在基线时为61 +/- 11 bpm，在峰值压力时为141 +/- 12 bpm。左室平均舒张压从基线时的12.3 +/- 2.6 mmHg降低到峰值应力时的9.0 +/- 2.3 mmHg（P = 0.0001）。隔垫和外侧环的基线E / E'分别为8.7 +/- 2.2和7.5 +/- 1.9，峰值应力期间的基线E / E'分别为8.3 +/- 3.1和7.9 +/- 3.5。隔膜或外侧环的E / E'均无明显变化（P = 0.55，P = 0.66）。左室平均舒张压和E / E'与多巴酚丁胺应激之间无显着相关性。结论：在左心室射血分数正常且无明显冠状动脉疾病的DSE患者中，多巴酚丁胺在峰值应力下舒张早期传递速度与舒张早期组织速度（E / E'）之比不能预测左室充盈压的变化。

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