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首页> 外文期刊>Echocardiography. >Ventricular diastolic function of ankylosing spondylitis patients by using conventional pulsed wave Doppler, myocardial performance index and tissue Doppler imaging.
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Ventricular diastolic function of ankylosing spondylitis patients by using conventional pulsed wave Doppler, myocardial performance index and tissue Doppler imaging.

机译：强直性脊柱炎患者的心室舒张功能通过使用常规脉冲波多普勒，心肌功能指数和组织多普勒成像。

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Objective: The aim of this study was to evaluate ventricular functions by using standard Doppler echocardiography (SDE), myocardial performance index (MPI), and pulsed wave tissue Doppler imaging (PW-TDI) in patients with ankylosing spondylitis (AS) and healthy controls. Methods: Forty-nine AS patients (38 +/- 11 years, 25 M/24 F) and 33 controls (36 +/- 9 years, 17 M/16 F) were studied. Two-dimensional, M-Mode, SDE, PW-TDI echocardiography examinations were performed. Spinal mobility was assessed by the Bath ankylosing spondylitis metrology index (BASMI) measurement. Patients were also evaluated using the Bath ankylosing spondylitis functional index (BASFI) and the Bath ankylosing spondylitis disease activity index (BASDAI). Results: Four control subjects and six AS patients met the left ventricular (LV) diastolic dysfunction (DD) criteria by using conventional Doppler echocardiography (p > 0.05). However, using PW-TDI method 22 patients in the AS group and six subjects in the control group were diagnosed to have LV DD (Em/Am < 1). Pseudonormalized pattern was present in 16 AS patients and two control subjects. Correlation analysis revealed significant moderate negative correlations between Em/Am and BASMI, age and body mass index (p < 0.05; r =-0.3, -0.6, and -0.4, respectively). No correlation was observed between Em/Am and disease duration, BASFI, BASDAI, CRP, and ESR. We could not detect any right ventricular function involvement either by conventional or by recently introduced echocardiography methods. The risk of developing LV DD was found to be 3.7 times higher in AS patients. Conclusion: When sensitive echocardiographic Doppler techniques such as MPI, TDI-derived MPI, and PW-TDI are utilized, DD can be detected in a significant proportion of patients with AS without cardiovascular (CV) disease which may contribute CV mortality in these patients.
机译：目的：本研究旨在通过对强直性脊柱炎（AS）和健康对照者使用标准多普勒超声心动图（SDE），心肌性能指数（MPI）和脉冲波组织多普勒成像（PW-TDI）评估心室功能。方法：研究了49例AS患者（38 +/- 11岁，25 M / 24 F）和33名对照（36 +/- 9岁，17 M / 16 F）。进行了二维，M型，SDE，PW-TDI超声心动图检查。通过巴斯强直性脊柱炎计量指数（BASMI）测量来评估脊柱活动度。还使用巴斯强直性脊柱炎功能指数（BASFI）和巴斯强直性脊柱炎疾病活动指数（BASDAI）对患者进行评估。结果：4名对照受试者和6名AS患者通过常规多普勒超声心动图检查符合左心室（LV）舒张功能障碍（DD）标准（p> 0.05）。但是，使用PW-TDI方法，AS组的22例患者和对照组的6名受试者被诊断为LV DD（Em / Am <1）。伪正常化模式存在于16名AS患者和两名对照受试者中。相关分析显示，Em / Am与BASMI，年龄和体重指数之间存在显着的中等负相关（p <0.05; r = -0.3，-0.6和-0.4）。在Em / Am与疾病持续时间，BASFI，BASDAI，CRP和ESR之间未发现相关性。我们无法通过传统方法或最近引入的超声心动图检查法检测到任何右心室功能受累。发现AS患者发生LV DD的风险高3.7倍。结论：使用MPI，TDI衍生的MPI和PW-TDI等灵敏的超声心动图多普勒技术时，可以在相当多的无心血管（CV）疾病的AS患者中检测到DD，这可能会导致这些患者的CV死亡率。

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