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首页> 外文期刊>Biochemical Genetics >Sequence analysis of the plasmid pGY1 harbored in Salmonella enterica serovar paratyphi A.
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Sequence analysis of the plasmid pGY1 harbored in Salmonella enterica serovar paratyphi A.

机译:肠炎沙门氏菌副伤寒沙门氏菌A中携带的质粒pGY1的序列分析。

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摘要

The cryptic plasmid pGY1, which is harbored by a clinical isolate of Salmonella enterica serovar Paratyphi A, was identified in a 9-year-old girl with paratyphoid fever in 2005, and its DNA sequence was determined. It is 3592 bp in length and had a G+C content of 43.3%. Three ORFs were predicted that share low similarity with hypothetical proteins in the GenBank database. pGY1 shared 36.6% sequence homology with the cryptic plasmid pIMVS1 from Salmonella typhimurium. Its unique sequence makes it attractive for further study to obtain insight into the evolutionary relationship of this plasmid with other Enterobacteriaceae plasmids.
机译:2005年在一名9岁的患有副伤寒的女孩中鉴定了由肠炎沙门氏菌血清副伤寒A的临床分离株携带的隐含质粒pGY1,并确定了其DNA序列。它的长度为3592 bp,G + C含量为43.3%。预测到三个ORF与GenBank数据库中的假设蛋白质具有低相似性。 pGY1与鼠伤寒沙门氏菌的隐含质粒pIMVS1具有36.6%的序列同源性。其独特的序列使其吸引人的进一步研究,以了解该质粒与其他肠杆菌科细菌质粒之间的进化关系。

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