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首页> 外文期刊>Bulletin du Cancer: Journal de l'Association Francaise pour l'Etude du Cancer >Rare tumors of the head and neck; on behalf of the REFCOR, the French Network of rare head and neck tumors [Cancers ORL rares et REFCOR, Réseau d'expertise fran?ais sur les cancers ORL rares]
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Rare tumors of the head and neck; on behalf of the REFCOR, the French Network of rare head and neck tumors [Cancers ORL rares et REFCOR, Réseau d'expertise fran?ais sur les cancers ORL rares]

机译：头颈部肿瘤少见;法国罕见头颈部肿瘤网络REFCOR代表[癌症ORL稀有肿瘤和REFCOR，法国法兰西岛上的癌症专科医师ORL罕见]

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摘要

Malignant tumors of the upper aerodigestive tract may be rare by their histology (sarcoma, variants of conventional squamous cell carcinomas) and/or location (sinuses, salivary glands, ear, of various histologies themselves). They represent less than 10% of head and neck neoplasms. The confirmation of their diagnosis often requires a medical expertise and sometimes biomolecular techniques complementary to classical histology and immunohistochemistry. Due to their location, their treatment often requires a specific surgical technique. Radiation therapy is indicated based on histoclinical characteristics common to other head and neck neoplasms but also incorporate grade. Further, the technique must often be adapted to take into account the proximity of organs at risk. For most histologies, chemotherapy is relatively inefficient but current molecular advances may allow to consider pharmaceutical developments in the coming years. The REFCOR, the French Network of head and neck cancers aims to organize and promote the optimal management of these rare and heterogeneous diseases, to promote research and clinical trials.
机译：上消化道恶性肿瘤的组织学（肉瘤，常规鳞状细胞癌的变种）和/或部位（鼻窦，唾液腺，耳朵，各种组织学本身）可能很少见。它们仅占头颈部肿瘤的不到10％。对其诊断的确认通常需要医学专业知识，有时还需要生物分子技术来补充经典组织学和免疫组织化学。由于其位置，其治疗通常需要特定的手术技术。根据其他头颈部肿瘤常见的组织学特征来指示放疗，但也要结合等级。此外，该技术通常必须适于考虑有风险的器官的邻近性。对于大多数组织学而言，化学疗法的效率相对较低，但是当前的分子进展可能会考虑在未来几年中药物的开发。法国头颈癌网络REFCOR旨在组织和促进对这些罕见和异质性疾病的最佳管理，以促进研究和临床试验。

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