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首页> 外文期刊>International journal of dermatology >Disseminated anetoderma in a patient with nodal Epstein-Barr virus-associated classical Hodgkin lymphoma: Anetodermic form of a concurrent discordant cutaneous marginal zone lymphoma
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Disseminated anetoderma in a patient with nodal Epstein-Barr virus-associated classical Hodgkin lymphoma: Anetodermic form of a concurrent discordant cutaneous marginal zone lymphoma

机译：淋巴结浸润性爱泼斯坦-巴尔病毒相关的经典霍奇金淋巴瘤患者的散发性皮肤病：并发性皮肤边缘区淋巴瘤的并发皮肤病形式

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摘要

Patients with a lymphoma have an increased risk of developing a second lymphoproliferative disorder. The association of nodal Hodgkin lymphoma and primary cutaneous marginal zone lymphoma (MALT type) is exceptional, and only very few cases have been documented. Anetoderma represents a circumscribed loss or rarefication of elastic fibers. Different underlying processes may result in anetoderma, including cutaneous marginal zone lymphoma. We report a 50-year-old male patient with Epstein-Barr virus (EBV)-associated nodal Hodgkin lymphoma who presented with disseminated anetodermic skin lesions. Biopsies of the skin lesions revealed a B-cell infiltrate containing monoclonal plasma cells but without detection of EBV. The skin lesions represent an anetodermic form of primary cutaneous marginal zone lymphoma. It is the first case report of an association of anetodermic cutaneous marginal zone lymphoma and a synchronous EBV-associated nodal Hodgkin lymphoma.
机译：淋巴瘤患者发生第二种淋巴增生性疾病的风险增加。淋巴结霍奇金淋巴瘤与原发性皮肤边缘区淋巴瘤（MALT型）的关联非常罕见，只有极少数病例被记录。脱皮皮肤病代表弹性纤维的界限性丢失或稀疏。不同的潜在过程可能导致皮肤病，包括皮肤边缘区淋巴瘤。我们报告了一名患有爱泼斯坦-巴尔病毒（EBV）相关的淋巴结霍奇金淋巴瘤的50岁男性患者，该患者呈现弥散性非脱铁皮病灶。皮肤病变的活检显示B细胞浸润​​，含有单克隆浆细胞，但未检测到EBV。皮肤病变代表原发性皮肤边缘区淋巴瘤的非脱氧形式。这是第一例关于非动脉粥样硬化性皮肤边缘区淋巴瘤与同步性EBV相关的淋巴结霍奇金淋巴瘤的报道。

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