...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Electrophoresis: The Official Journal of the International Electrophoresis Society >ACUTE-PHASE PROTEINS IN PERINATAL HUMAN PLASMA
【24h】

ACUTE-PHASE PROTEINS IN PERINATAL HUMAN PLASMA

机译：人鼻血浆中的急性相蛋白

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Plasma from eight newborns (4 pre-term and 4 full-term) with early-onset (< 72 h) sepsis and six apparently healthy controls was analyzed. The presence of spots identified as haptoglobin and serum amyloid A protein was the electrophoretic result most consistently associated with disease. Time Course monitoring showed rises, peaks and declines of spot intensity as expected for acute-phase proteins induced by transient stimuli. Haptoglobin beta chains appear to be undersialated in pre-term newborns, whereas post-translational modifications of alpha chains and serum amyloid A protein are similar to those observed in adules. The undersialation of beta chain and occurrence of alpha chain phenotypes different from those found in maternal serum indicate that perinatal haptoglobin originates from neonatal synthesis. [References: 20]
机译：分析了来自8个新生儿（4个早产和4个足月）伴早发性脓毒症（<72小时）的血浆和6个明显健康的对照组的血浆。鉴定为触珠蛋白和血清淀粉样蛋白A蛋白的斑点是与疾病最一致的电泳结果。时程监测显示，瞬时刺激诱导的急性期蛋白可预期斑点强度的上升，下降和下降。 Haptoglobinβ链在早产儿中似乎未充分唾液酸化，而α链和血清淀粉样蛋白A蛋白的翻译后修饰与在腺管中观察到的相似。 β链唾液酸化和与孕妇血清中发现的α链表型不同，表明围产期触珠蛋白源于新生儿合成。 [参考：20]

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号