Regulation and function of innate and adaptive interleukin-17-producing cells

Hirota K.; Ahlfors H.; Duarte J.H.; Stockinger B.

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Regulation and function of innate and adaptive interleukin-17-producing cells

机译：先天和适应性白介素17产生细胞的调节和功能

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Interleukin-17 (IL-17)-mediated immune responses play a crucial role in the mucosal host defence against microbial and fungal pathogens. However, the chronic activation of IL-17-producing T helper cells can cause autoimmune disease. In addition, recent studies have highlighted key roles of innate cell-mediated IL-17 responses in various inflammatory settings. Besides inflammation, there have also been intriguing findings regarding the involvement of IL-17 responses in the pathogenesis of cardiovascular diseases and tumour formation. Here, we discuss the latest discoveries in regulation and function of innate and adaptive IL-17-producing cells.

机译：白介素17（IL-17）介导的免疫反应在粘膜宿主防御微生物和真菌病原体中起着至关重要的作用。但是，产生IL-17的T辅助细胞的长期激活会引起自身免疫性疾病。此外，最近的研究突出了先天细胞介导的IL-17反应在各种炎症环境中的关键作用。除炎症外，关于IL-17反应参与心血管疾病的发病机制和肿瘤形成也有有趣的发现。在这里，我们讨论先天性和自适应性IL-17产生细胞的调节和功能的最新发现。

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《EMBO reports》 |2012年第2期|共8页
作者
Hirota K.; Ahlfors H.; Duarte J.H.; Stockinger B.;
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正文语种 eng
中图分类分子生物学;
关键词
autoimmune; IL-17; mucosal host defence; plasticity; T _H17;

机译：自身免疫;IL-17;粘膜宿主防御;可塑性;T _H17;

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1. Regulation and function of innate and adaptive interleukin-17-producing cells [J] . Hirota K., Ahlfors H., Duarte J.H., EMBO reports . 2012,第2期

机译：先天和适应性白介素17产生细胞的调节和功能
2. The messenger between worlds: the regulation of innate and adaptive type-2 immunity by innate lymphoid cells [J] . Scanlon S. T., McKenzie A. N. J. Clinical and experimental allergy : . 2015,第1期

机译：世界之间的使者：先天淋巴样细胞对先天性和适应性2型免疫的调节
3. Regulation of Macrophage and Dendritic Cell Function by Chondroitin Sulfate in Innate to Antigen-Specific Adaptive Immunity [J] . Sonoko Hatano, Hideto Watanabe Frontiers in Immunology . 2020,第1期

机译：软骨素硫酸盐在先天血清硫酸盐与抗原特异性自适应免疫调节巨噬细胞和树突细胞功能
4. The N-and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity [C] . Yurong Li, Hui Peng, Gencheng Han, International conference of molecular simulations and applied informatics technologies . 2012

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5. Linkages of innate and adaptive immunity: Differential regulation of dendritic cell functions by surfactant proteins A and D. [D] . Brinker, Karen Gail. 2002

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6. Regulation and function of innate and adaptive interleukin-17-producing cells [O] . Keiji Hirota, Helena Ahlfors, João H Duarte, 2012

机译：先天和自适应白介素17产生细胞的调节和功能。
7. Innate and Adaptive Immune Functions of Peyer's Patch Monocyte-Derived Cells Article Innate and Adaptive Immune Functions of Peyer's Patch Monocyte-Derived Cells [O] . Bonnardel Johnny, Da Silva Clément, Henri Sandrine, 2015

机译：Peyer's Patch单核细胞衍生细胞的先天性和适应性免疫功能Article of Peyer's Patch单核细胞衍生细胞的先天性和适应性免疫功能

Regulation and function of innate and adaptive interleukin-17-producing cells

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