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Correlation of early postoperative blood glucose levels with postoperative complications, hospital costs, and length of hospital stay in patients with gastrointestinal malignancies

机译:胃肠道恶性肿瘤患者术后早期血糖水平与术后并发症,住院费用和住院时间的关系

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摘要

Early postoperative hyperglycemia in non-diabetic patients is an important risk factor affecting postoperative complications and mortality. This study aimed at investigating the effects of early postoperative hyperglycemia on postoperative complications, hospital costs, and length of hospital stay in non-diabetic patients with gastrointestinal malignancies; data of 1,015 non-diabetic patients with gastrointestinal malignancies, who underwent surgical intervention between January 2010 and January 2012, were retrospectively evaluated. Records on fasting plasma glucose (FPG), liver function, and kidney function were collected before and one day after surgery. Correlation of early postoperative FPG levels with postoperative complications, hospital costs, and length of hospital stay was further assessed in non-diabetic patients with gastrointestinal malignancies. One day after surgery, FPG results were significantly increased compared to preoperative values. FPG levels greater than or equal to 9.13 mmol/L (or 164.34 mg/dL) were associated with significant increases in the incidence of postoperative complications, length of hospital stay, and hospital costs. An association is shown between FPG and postoperative hyperglycemia in non-diabetic patients undergoing surgery for gastrointestinal malignancies. Significant increases in postoperative complications among these patients suggest that measurement of early postoperative FPG levels is critical to identify patients with postoperative hyperglycemia.
机译:非糖尿病患者术后早期高血糖是影响术后并发症和死亡率的重要危险因素。这项研究旨在调查术后早期高血糖对非糖尿病胃肠道恶性肿瘤患者的并发症,住院费用和住院时间的影响;回顾性分析2010年1月至2012年1月间接受手术治疗的1,015例非糖尿病胃肠道恶性肿瘤患者的数据。在手术前和手术后一天收集空腹血糖(FPG),肝功能和肾功能的记录。在非糖尿病胃肠道恶性肿瘤患者中,进一步评估了术后早期FPG水平与术后并发症,住院费用和住院时间的相关性。术后一天,与术前相比,FPG结果显着增加。 FPG水平大于或等于9.13 mmol / L(或164.34 mg / dL)与术后并发症发生率,住院时间和住院费用的显着增加有关。在接受胃肠道恶性肿瘤手术的非糖尿病患者中,FPG与术后高血糖之间存在关联。这些患者术后并发症的显着增加表明,早期术后FPG水平的测量对于确定术后高血糖患者至关重要。

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