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Endocrine Aspects of Post-traumatic Stress Disorder and Implications for Diagnosis and Treatment

机译:创伤后应激障碍的内分泌方面及其对诊断和治疗的意义

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摘要

Post-traumatic stress disorder (PTSD) is a serious, multisystem disorder with multiple medical comorbidities. This article reviews the current literature on the endocrine aspects of PTSD, specifically hypothalamic-pituitary-adrenal axis alterations indicative of low cortisol and increased glucocorticoid sensitivity, and the proposed mechanisms whereby these alterations increase risk or reflect pathophysiology. Discussion includes novel treatment innovations and directions for future research.
机译:创伤后应激障碍(PTSD)是一种严重的多系统疾病,涉及多种医学合并症。本文回顾了有关创伤后应激障碍的内分泌方面的最新文献,特别是下丘脑-垂体-肾上腺轴改变提示皮质醇水平低和糖皮质激素敏感性增加,以及所提出的机制,这些改变增加了风险或反映了病理生理学。讨论包括新颖的治疗方法创新和未来研究的方向。

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