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Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State

机译:糖尿病酮症酸中毒和高血糖高渗状态

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Diabetic ketoacidosis (DKA) and the hyperglycemic hyperosmolar state (HHS) are potentially fatal hyperglycemic crises that occur as acute complications of uncontrolled diabetes mellitus. The authors provide a review of the current epidemiology, precipitating factors, pathogenesis, clinical presentation, evaluation, and treatment of DKA and HHS. The discovery of insulin in 1921 changed the life expectancy of patients with diabetes mellitus dramatically. Today, almost a century later, DKA and HHS remain significant causes of morbidity and mortality across different countries, ages, races, and socioeconomic groups and a significant economic burden for society.
机译:糖尿病性酮症酸中毒(DKA)和高血糖高渗血症(HHS)是潜在的致命高血糖危机,发生于不受控制的糖尿病的急性并发症。作者对DKA和HHS的当前流行病学,诱发因素,发病机理,临床表现,评估和治疗进行了综述。 1921年胰岛素的发现极大地改变了糖尿病患者的预期寿命。今天,大约一个世纪之后,DKA和HHS仍然是不同国家,年龄,种族和社会经济群体的发病率和死亡率的重要原因,并给社会带来了巨大的经济负担。

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