Testosterone Administration in Older Men

MatsumotoA.M.

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Testosterone Administration in Older Men

机译：老年男性的睾丸激素管理

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The only indication for testosterone administration in older men is testosterone replacement therapy for male hypogonadism. Compared with young hypogonadal men, the diagnosis and management of male hypogonadism in older men is more challenging. Both the clinical manifestations of androgen deficiency and low testosterone levels may be caused or modified by comorbid illnesses that occur and medications taken more frequently by older men, resulting in a greater likelihood for overdiagnosis of hypogonadism and subsequent inappropriate use of and inadequate response to testosterone treatment. It is important to use a systematic, holistic approach to the diagnosis and management of older men with hypogonadism.

机译：老年男性服用睾丸激素的唯一指征是男性性腺功能减退的睾丸激素替代疗法。与年轻的性腺机能减退男性相比，老年男性的性腺机能减退的诊断和治疗更具挑战性。雄激素缺乏症和睾丸激素水平低下的临床表现均可能是由并发疾病引起的，或由老年男性更频繁地服用药物引起，从而导致对性腺功能低下症的过度诊断以及随后对睾丸激素治疗的不适当使用和反应不足的可能性更大。。重要的是要使用系统，整体的方法来诊断和治疗性腺功能减退的老年男性。

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《Endocrinology and Metabolism Clinics of North America》 |2013年第2期|共16页
作者
MatsumotoA.M.;
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正文语种 eng
中图分类内分泌腺疾病及代谢病;
关键词
Aging; Diagnosis; Hypogonadism; Testosterone; Treatment;

机译：衰老;诊断;性腺功能减退;睾丸激素;治疗;

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2. Letter to the Editor: "Long-Term Testosterone Administration on Insulin Sensitivity in Older Men With Low or Low-Normal Testosterone Levels". [J] . Sandeep Dhindsa, Husam Ghanim, Paresh Dandona The journal of clinical endocrinology and metabolism . 2018,第5期

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4. Induction of rat germ cells apoptosis by Testosterone Undecanoate and Depot Medroxyprogesterone Acetate administrations and its correlation to the Sperm Concentration [C] . N. Moeloek, Asmarinah, N.C. Siregar, International Congress of Andrology . 2009

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5. Chronic Testosterone Deprivation Sensitizes the Middle-aged Rat Brain to Damaging Effects of Testosterone Replacement [D] . Smith, Charity. 2020

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机译：口服睾丸激素后气相色谱-燃烧-同位素比质谱分析尿液中四种睾丸酮代谢物和孕烯二醇
8. Klinefelter's Syndrome: Examination of Thyroid Function and the TSH and PRL Responses to Thyrotropin-Releasing Hormone Prior to and after Testosterone Administration. [R] . Burman, K. D., Dimond, R. C., Noel, G. L., 1975

机译：Klinefelter综合征：在睾酮给药之前和之后检查甲状腺功能和TsH和pRL对促甲状腺激素释放激素的反应。

Testosterone Administration in Older Men

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