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Permeability of Human Tooth Surfaces Studied In Vitro by Electrochemical Impedance Spectroscopy

机译：电化学阻抗谱法体外研究人牙表面的渗透性

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Electrochemical Faradaic impedance spectroscopy was applied to evaluate dependence of the electrical resistance on human teeth. The experiments were performed using iodide anions as a redox probe to model permeability of teeth for fluoride upon an iontophoresis process. Tooth molars were used - as these are teeth most affected by tooth decay processes in vivo. Teeth compared included sound molars - with no evidence of pit and fissure decay, teeth with pits and fissures regarded 'clinically' as showing signs of decay, and teeth with crowns removed to present exposed dentin surfaces. A difference of more than an order of magnitude in electrical resistance was observed between sound molars and those regarded as showing evidence of tooth decay processes. Sound dentin, as expected from structural considerations demonstrated significantly lower resistance when compared to sound molars. Importantly, the difference in tooth resistance measured between carious and sound molars was shown to be much more representative of their structural integrity than comparison of digitally processed images of the teeth. The results support the utility of electrochemical Faradaic impedance spectroscopy for the development of understanding on how tooth electrical resistance may vary according to structural changes. This understanding may be useful to continued refinements in the use of electrical resistance measures as caries diagnostics and support generically the potential for iontophoretic processes in in-office fluoride treatments of teeth.
机译：电化学法拉第阻抗光谱法用于评估电阻对人牙齿的依赖性。使用碘阴离子作为氧化还原探针进行实验，以模拟离子电渗过程中氟化物对牙齿的渗透性。使用了臼齿-因为这些是在体内受蛀牙过程影响最大的牙齿。比较的牙齿包括健全的臼齿-没有凹陷和裂痕腐烂的迹象，带有凹陷和裂痕的牙齿在临床上被视为显示腐烂迹象，并且去除了冠的牙齿呈现出暴露的牙本质表面。在声磨牙和被认为显示蛀牙迹象的磨牙之间，观察到电阻的差异超过一个数量级。从结构上的考虑，合理的牙本质与耐磨牙相比显示出明显更低的抵抗力。重要的是，与比较数字化处理过的牙齿图像相比，在龋齿和声音磨牙之间测得的牙齿阻力差异更能代表其结构完整性。该结果支持电化学法拉第阻抗谱用于了解牙齿电阻如何根据结构变化而发展的实用性。这种理解可能有助于继续改进电阻测量方法作为龋齿诊断的用途，并普遍支持在牙齿进行办公室氟化物治疗中离子电渗疗法的潜力。

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