Introduction of Ketamine as a G-Quadruplex-Binding Ligand Using Platinum Nanoparticle Modified Carbon Paste Electrode

Zahra Bagheryan; Jahan-Bakhsh Raoof; Reza Ojani; Ezat Hamidi-Asl

首页> 外文期刊>Electroanalysis >Introduction of Ketamine as a G-Quadruplex-Binding Ligand Using Platinum Nanoparticle Modified Carbon Paste Electrode

【24h】

Introduction of Ketamine as a G-Quadruplex-Binding Ligand Using Platinum Nanoparticle Modified Carbon Paste Electrode

机译：用铂纳米粒子修饰的碳糊电极引入氯胺酮作为G-四链体结合配体

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

We designed an electrochemical platform by modifying a carbon paste electrode (CPE) with platinum nanoparticles to study the interaction between ketamine and the G-quadruplex structure of human telomeric DNA (G4HTD). The drug ketamine (Kt) was used as the model ligand and its ability for stabilizing the G-quadruplex structure was examined. The modified CPE (NPtCPE) was characterized by differential pulse voltammetry (DPV) and atomic force microscopy (AFM). The interaction of Kt with G4HTD was studied by DPV and the DPV current decreased with increasing Kt concentration. The results from UV-vis and circular dichroism (CD) spectroscopy showed a prominent intercalation mode between G4HTD and Kt.

机译：我们通过用铂纳米颗粒修饰碳糊电极（CPE）设计了一个电化学平台，以研究氯胺酮与人类端粒DNA（G4HTD）的G-四链体结构之间的相互作用。将药物氯胺酮（Kt）用作模型配体，并研究了其稳定G-四链体结构的能力。通过差示脉冲伏安法（DPV）和原子力显微镜（AFM）对改性CPE（NPtCPE）进行了表征。通过DPV研究了Kt与G4HTD的相互作用，并且DPV电流随着Kt浓度的增加而降低。紫外可见光谱和圆二色性（CD）光谱的结果表明，G4HTD和Kt之间存在明显的嵌入模式。

著录项

来源
《Electroanalysis》 |2013年第12期|共9页
作者
Zahra Bagheryan; Jahan-Bakhsh Raoof; Reza Ojani; Ezat Hamidi-Asl;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类电化学、电解、磁化学;
关键词
G-quadruplex; Ketamine; Telomere; Anti-cancer; Platinum nanoparticle;

机译：G-四链体;氯胺酮;端粒;抗癌;铂纳米粒子;

相似文献

外文文献
中文文献
专利

1. Introduction of Ketamine as a G-Quadruplex-Binding Ligand Using Platinum Nanoparticle Modified Carbon Paste Electrode [J] . Zahra Bagheryan, Jahan-Bakhsh Raoof, Reza Ojani, Electroanalysis . 2013,第12期

机译：用铂纳米粒子修饰的碳糊电极引入氯胺酮作为G-四链体结合配体
2. Simultaneous voltammetric determination of paracetamol, cetirizine and phenylephrine using a multiwalled carbon nanotube-platinum nanoparticles nanocomposite modified carbon paste electrode [J] . Pramod K. Kalambate, Ashwini K. Srivastava Sensors and Actuators . 2016,第octa期

机译：碳纳米管-铂纳米颗粒纳米复合修饰碳糊电极同时测定对乙酰氨基酚，西替利嗪和去氧肾上腺素
3. Polyurethane-doped platinum nanoparticles modified carbon paste electrode for the sensitive and selective voltammetric determination of free copper ions in biological samples [J] . Abd El-Raheem Hany, Hassan Rabeay Y. A., Khaled Rehab, Microchemical Journal: Devoted to the Application of Microtechniques in all Branches of Science . 2020,第1期

机译：聚氨酯掺杂铂纳米颗粒改性碳浆料电极，用于敏感和选择性伏安法测定生物样品中的游离铜离子
4. A novenovel electrochemical sensor for formaldehyde based on Platinum nanoparticle / L-alanine modified glassy carbon electrode [C] . Jiahong He, Yansong Kuang, Zhongrong Song, The 14th Annual conference of the Chinese Society of Micro-Nano technology; The 3rd International conference of the Chinese Society of Micro-Nano technology; The 6th International workshop on innovation and commercialization of Micro amp; Nanotechnology . 2012

机译：基于铂纳米粒子/ L-丙氨酸修饰的玻碳电极的novenovel甲醛电化学传感器
5. PART I: ANODIC OXIDATION PATHWAYS OF SUBSTITUTED INDOLES. PART II: ANALYTICAL APPLICATIONS OF CHEMICALLY MODIFIED CARBON PASTE ELECTRODES. [D] . CHEEK, GRAHAM TERRY. 1978

机译：第一部分：取代的吲哚的阳极氧化途径。第二部分：化学改性的碳糊电极的分析应用。
6. Green synthesized silver nanoparticle modified carbon paste electrode for SWAS voltammetric simultaneous determination of Cd(II) and Pb(II) in Bahir Dar Textile discharged effluent [O] . Meareg Amare, Awoke Worku, Adane Kassa, 2020

机译：绿色合成银纳米粒子改性碳浆电极用于SWAS伏安同时测定Bahir Dar Textile排出流出物中的CD（II）和PB（II）
7. Silica gel/gold nanoparticles/(NS)2 ligand nanoporous platform-modified ionic liquid carbon paste electrode for potentiometric ultratrace assessment of Ag(I) [O] . S. Ramezani, M. H. Mashhadizadeh, M. Ghobadi, 2016

机译：硅胶/金纳米颗粒/（NS）2配体纳米多孔平台改性离子液体碳浆电极，用于AG的电位超时评估（I）
8. Chemically Modified Electrodes. XIV. Attachment of Reagents to Oxide-Free Glassy Carbon Surfaces. Electroactive RF Polymer Films on Carbon and Platinum Electrodes. [R] . nowak, r. schultz, f. a. 1978

机译：化学修饰电极。十四。试剂与无氧化物玻碳表面的连接。碳和铂电极上的电活性RF聚合物薄膜。

Introduction of Ketamine as a G-Quadruplex-Binding Ligand Using Platinum Nanoparticle Modified Carbon Paste Electrode

摘要

著录项

相似文献

相关主题

期刊订阅